Outcomes following SARS-CoV-2 infection in patients with chronic liver disease: An international registry study

Abstract

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RETRACTED ARTICLE: Efficacy of favipiravir in COVID-19 treatment: a multi-center randomized study

“…The food and drug administration (FDA) granted emergency approval to allow hospitals to use chloroquine and hydroxychloroquine for treatment of COVID-19, and these drugs have been used as standard of care in some countries [ 4 – 24 ]. However, many questions remain about the efficacy of chloroquine in treatment of COVID-19 [ 6 – 16 ]…”

RETRACTED ARTICLE: Do Zinc Supplements Enhance the Clinical Efficacy of Hydroxychloroquine?: a Randomized, Multicenter Trial

“…There is a debate in the literature regarding the efficacy of CQ and HCQ in the treatment of COVID-19 infection [9][10][11][12]. Adding azithromycin to CQ and HCQ was reported to reduce the complications and fatality rates, and reduce the viral load in COVID-19 patients [7][8][9][10][11][12][13][14][15][16][17][18][19][20][21][22]. These reports resulted in emerged ideas calling for combining CQ and HCQ with other drugs in the treatment of COVID-19.…”

“…Zinc is essential for different cellular and enzymatic activities, as well as being a necessary cofactor for many viral proteins [15][16][17][18][19][20][21][22][23][24][25]. Zinc was also proved to inhibit RNAdependent RNA polymerase of SARS-CoV in cell culture [17].…”

SARS-CoV-2 Virus Manifestations in the Gastrointestinal Tract: Therapeutic Implications

“…Vice vera, COVID-19 can lead to decompensation of a pre-existing liver damage, so some guidelines recommend testing for COVID-19 in decompensating liver cirrhosis without any other signs of COVID-19-like respiratory symptoms. Beyond that, distinguishing whether the higher rate of death in liver patients with COVID-19 is because of the underlying liver disease or different relevant comorbidities is challenging [ 14 , 48 , 49 , 50 ].…”