Outbreak of a Multiresistant Klebsiella pneumoniae Strain in an Intensive Care Unit: Antibiotic Use as Risk Factor for Colonization and Infection

Risk factors for healthcare-associated infection in pediatric intensive care units: a systematic review

“…Abstracts for which there was no agreement as to the inclusion were analyzed jointly and the decision was made by consensus. Thus, 84 (80 articles and four theses) were ob-tained for detailed reading by the same two authors independently 27,28,29,30,31,32,33,34,35,36,37,38,39,40,41,42,43,44,45,46,47,48,49,50,51,52,53,54,55,56,57,58,59,60,61,62,63,64,65,66,67,68,69,70,71,72,73,74,75,76,77,…”

Structural Basis of a Physical Blockage Mechanism for the Interaction of Response Regulator PmrA with Connector Protein PmrD from Klebsiella pneumoniae

“…The increasing antibiotic resistance to Klebsiella pneumonia bacteria, a common cause of nosocomial bacterial infections causing pneumonia and urinary tract infections, especially in immunocompromised patients (12), led us to investigate how the virulence and drug resistance persist via the associated TCS. Similar to most response regulators, the PmrA of K. pneumoniae belonging to the OmpR-PhoB family is composed of an N-terminal receiver domain ( Fig.…”

“Isolation and Characterization of Lactose and Non- Lactose Fermenting Bacteria From Tertiary Care Hospital and Their Antimicrobial Susceptibility Test”

“…They have been detected in other Gram-negative bacilli such as Salmonella species, Proteus spp., P. aeruginosa, and other Enteobacteiaceae [6]. Resistant to beta-lactamase is most commonly associated with the production of high levels of naturally produced cephalosporinase [7]. Carbapenem resistance is primarily caused by two mechanisms, either by reducing intracellular concentration or by hydrolysis of the drug [8].…”