Osteoporosis/osteopenia as an independent factor associated with periodontitis in postmenopausal women: a case–control study

Abstract

These findings highlight that postmenopausal women with osteoporosis/osteopenia had a greater chance of presenting periodontitis than those with normal bone mineral density, particularly among nonusers of osteoporosis medications and women with a greater number of remaining teeth.

Assessment the Relationship between Osteoporosis with Tooth Loss and Dry Mouth in Women with Osteoporosis

“…Darcy et al [19] & Passos et al [20] indicate the relationship between osteoporosis and tooth loss, which does not match with our studies. In Lundstram's [21] study also examined the relationship between osteoporosis and the number of missing teeth and the results showed no significant difference between osteoporosis and the number of missing teeth and results also match with the study.…”

Initial changes in alveolar bone volume for sham-operated and ovariectomized rats in ligature-induced experimental periodontitis

“…There exists accumulating evidence that a relationship may exist [8][9][10][11][12][13][14]; however to date, no animal or histological study has fully confirmed this possible relationship. Therefore, we sought to utilize an animal model to perform histological assessment and to characterize alveolar bone loss in an osteoporotic model by creating OVX animals and comparing them to control sham-operated animals for periodontal changes from 0 to 11 days following a ligature-induced periodontitis animal model.…”

“…Interestingly, growing clinical evidence has suggested that a relationship between osteoporosis and periodontal disease exist [8][9][10][11][12][13][14]. In one of the first well-documented studies investigating this relationship, it was found that osteoporosis had no significant effect with respect to plaque and gingival bleeding but was associated with a significantly greater loss of attachment in osteoporotic women [10].…”

Comorbidity of periodontal disease: two sides of the same coin? An introduction for the clinician

“…The most prevalent form is postmenopausal osteoporosis, the possible association of which with PDIS has been examined in several clinical studies. The majority of these studies have been cross-sectional and with few participants, all postmenopausal women [68–75]. A recent cross-sectional study from Taiwan including 35,127 osteoporosis patients and 50,498 healthy controls showed that PDIS was associated with an increased risk of osteoporosis (odds ratio [OR] = 1.29) after adjustment for sex, age, and comorbidity, and that the risk increased with increased degree of periodontal inflammation [76].…”