Osteoconduction of a stoichiometric and bovine hydroxyapatite bilayer‐coated implant

Hayami, Takashi; Hontsu, Shigeki; Higuchi, Yuichi; Nishikawa, Hiroaki; Kusünoki, Masanobu

doi:10.1111/j.1600-0501.2010.02057.x

Cited by 21 publications

(23 citation statements)

References 3 publications

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“…In particular, by PLD apatite has been deposited starting from simple, LiO 2 -and CIG-doped ovine and bovine bone, MgF 2 , and Mg doped bovine bone, simple and titanium doped ovine dentine and human dentine. Further experiments about deposition of "natural apatite" by PLD have also been reported, tested in vitro and in vivo, but without suitable description of the apatite source and the deposition procedures [70,71].…”

Section: Multi-substituted Coatings and Deposition From Biogenic Sourcesmentioning

confidence: 99%

A Review on Ionic Substitutions in Hydroxyapatite Thin Films: Towards Complete Biomimetism

2018

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Plasma sprayed coatings composed of stoichiometric hydroxyapatite have been extensively used to improve integration of metallic implants in the host bone, as hydroxyapatite (HA) is normally regarded as similar to the mineralized phase of bone. However, these coatings exhibited several drawbacks that limited their success. On the one hand biological apatite is a carbonated-HA, containing significant amounts of foreign ions, having low crystallinity and a small crystals size. This means that it differs from stoichiometric HA in terms of composition, stoichiometry, crystallinity degree, crystal size/morphology and, as a direct consequence, solubility, and ions release in the peri-implant environment. On the other hand, thick plasma sprayed coatings can undergo cracking and delamination and are scarcely uniform. For these reasons, research is pushing into two directions: (i) Increasing the similarity of apatite coatings to real bone, and (ii) exploring deposition by alternative plasma assisted techniques, allowing to achieve thin films, and having superior adhesion and a better control over the coating composition. In this article, we review the latest advances in the field of plasma-assisted deposition of ion-substituted hydroxyapatite thin films, highlighting the state of the art, the limitations, potentialities, open challenges, and the future scenarios for their application.

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Section: Multi-substituted Coatings and Deposition From Biogenic Sourcesmentioning

confidence: 99%

A Review on Ionic Substitutions in Hydroxyapatite Thin Films: Towards Complete Biomimetism

2018

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“…The ceramic nano-materials selected for manufacturing coatings on Ti implants are those that have been classified as bioactive and mainly include HA, [182][183][184] bioactive glass, 185 and other calcium phosphate compounds. 186,187 Nano-HA is probably the most preferable material used as a coating for Ti, Ti alloys and stainless steel implants because it is similar to the inorganic component of bone.…”

Section: Dental Implantsmentioning

confidence: 99%

Review of Nanomaterials in Dentistry: Interactions with the Oral Microenvironment, Clinical Applications, Hazards, and Benefits

et al. 2015

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Interest in the use of engineered nanomaterials (ENMs) as either nanomedicines or dental materials/devices in clinical dentistry is growing. This review aims to detail the ultrafine structure, chemical composition, and reactivity of dental tissues in the context of interactions with ENMs, including the saliva, pellicle layer, and oral biofilm; then describes the applications of ENMs in dentistry in context with beneficial clinical outcomes versus potential risks. The flow rate and quality of saliva are likely to influence the behavior of ENMs in the oral cavity, but how the protein corona formed on the ENMs will alter bioavailability, or interact with the structure and proteins of the pellicle layer, as well as microbes in the biofilm, remains unclear. The tooth enamel is a dense crystalline structure that is likely to act as a barrier to ENM penetration, but underlying dentinal tubules are not. Consequently, ENMs may be used to strengthen dentine or regenerate pulp tissue. ENMs have dental applications as antibacterials for infection control, as nanofillers to improve the mechanical and bioactive properties of restoration materials, and as novel coatings on dental implants. Dentifrices and some related personal care products are already available for oral health applications. Overall, the clinical benefits generally outweigh the hazards of using ENMs in the oral cavity, and the latter should not prevent the responsible innovation of nanotechnology in dentistry. However, the clinical safety regulations for dental materials have not been specifically updated for ENMs, and some guidance on occupational health for practitioners is also needed. Knowledge gaps for future research include the formation of protein corona in the oral cavity, ENM diffusion through clinically relevant biofilms, and mechanistic investigations on how ENMs strengthen the tooth structure.

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“…Although these were the differences, stoichiometric HA has been widely used as hard tissue substitute or coating material for hard tissue implants, since it is the most similar material to the inorganic component of the bones i.e. bone mineral [4][5][6][7][8].…”

Section: Introductionmentioning

confidence: 99%

Bone-like hydroxyapatite precipitated from 10×SBF-like solution by microwave irradiation

Demirtaş

Kaynak

Gümüşderelı́oğlu

2015

Materials Science and Engineering: C

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Osteoconduction of a stoichiometric and bovine hydroxyapatite bilayer‐coated implant

Cited by 21 publications

References 3 publications

A Review on Ionic Substitutions in Hydroxyapatite Thin Films: Towards Complete Biomimetism

A Review on Ionic Substitutions in Hydroxyapatite Thin Films: Towards Complete Biomimetism

Review of Nanomaterials in Dentistry: Interactions with the Oral Microenvironment, Clinical Applications, Hazards, and Benefits

Bone-like hydroxyapatite precipitated from 10×SBF-like solution by microwave irradiation

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