Osmotic-driven mass transport of water: Impact on the adhesiveness of hydrophilic polymers

Borde, Annika; Bergstrand, Anna; Gunnarsson, Cecilia; Larsson, Anette

doi:10.1016/j.jcis.2009.09.051

Cited by 12 publications

(10 citation statements)

References 11 publications

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“…In this work, as bio-adhesive model system Carbopol (or Carbopol mixed with NaCl) tablet was used, whereas the mucosa was mimicked by an aqueous agarose gel (1% (w/w)), similarly to Borde et al who exploited this gel for its ability to be loaded with salts or varied in concentration (Borde et al, 2010). Carbopol 974-P NF containing maximum 2.5% sulfated ash was purchased from Noveon (USA).…”

Section: Methodsmentioning

confidence: 99%

“…(Borde et al, 2010), 1% (w/w) agarose gels were prepared by mixing agarose powder and Milli-Q water, and then heated under magnetic stirring until boiling. The beaker containing the solution was covered with an aluminum foil to limit the water evaporation and before molding the agarose content corrected to be at 1% w/w.…”

Section: Agarose Gel Preparationmentioning

confidence: 99%

“…To validate the reliability of the experimental set up used in this study, first of all the experiment proposed by Borde et al (2010), which was designed in order to study the effect of contact time on the detachment force and weight gain, was reproduced. The tests carried out in this work confirmed a good agreement in terms of force (not reported) and weight gain (Fig.…”

Section: Pure Carbopol Tabletsmentioning

confidence: 99%

“…According to these hypotheses there will be a quick dehydration that enhances the mucosa adhesive properties (Mortazavi & Smart, 1993) and generates a suction force. This last theory has attracted the attention of several researchers that, despite enlightening different aspects and developing different techniques of analysis, have tried to quantify the water transport and to relate it to the adhesion force (Borde, Bergstrand, Gunnarsson, & Larsson, 2010;Mortazavi & Smart, 1993). One of the most frequently applied methods to quantify the adhesion force is based on the use of a Texture Analyzer (T.A.…”

Section: Introductionmentioning

confidence: 99%

“…The full symbols represent data obtained previously(Borde et al, 2010), the open symbols data produced in the frame of the present work. .…”

mentioning

confidence: 99%

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