Orthostatic stress causes immediately increased blood pressure variability in women with vasovagal syncope

Reulecke, Sina; Charleston-Villalobos, S.; Voss, Andreas; González-Camarena, R.; González-Hermosillo, Jesús Antonio; Gaitán-González, Mercedes J.; Hernández-Pacheco, Guadalupe; Schroeder, Rico

doi:10.1016/j.cmpb.2015.12.005

Cited by 22 publications

(18 citation statements)

References 29 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…We also made an attempt to differentiate the patients who developed syncope during the passive phase of HUTT from those who required NTG provocation. The application of entropy measures to assess changes in heart rate dynamics has been extensively investigated [ 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 , 9 , 10 , 17 , 20 , 21 , 22 , 23 , 24 , 40 ]. Wejer et al [ 20 ] measured the complexity of cardiovascular regulation during tilt test in patients suffered from VVS and healthy subject using Shannon Entropy.…”

Section: Discussionmentioning

confidence: 99%

“…Those authors suggested that a loss of complexity of RRI is directly connected with disease. In the analysis of complexity of RRI and blood pressure conducted on women suffering from VVS Reulecke et al [ 24 ] also observed significant decreasing of entropy measure of RRI in response to the tilt. The mentioned observations are compatible with decreasing of HRV and thus with increased sympathetic activity in response to the tilt.…”

Section: Discussionmentioning

confidence: 99%

“…Entropy measures are widely used for assessment of biosignals’ irregularity and complexity [ 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 ]. The computation of entropy based on the first fundamental definitions needed a large number of data to achieve convergence.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Entropy Measures in Analysis of Head up Tilt Test Outcome for Diagnosing Vasovagal Syncope

Buszko

Piątkowska

Koźluk

et al. 2018

Entropy

View full text Add to dashboard Cite

The paper presents possible applications of entropy measures in analysis of biosignals recorded during head up tilt testing (HUTT) in patients with suspected vasovagal syndrome. The study group comprised 80 patients who developed syncope during HUTT (57 in the passive phase of the test (HUTT(+) group) and 23 who had negative result of passive phase and developed syncope after provocation with nitroglycerine (HUTT(−) group)). The paper focuses on assessment of monitored signals' complexity (heart rate expressed as R-R intervals (RRI), blood pressure (sBP, dBP) and stroke volume (SV)) using various types of entropy measures (Sample Entropy (SE), Fuzzy Entropy (FE), Shannon Entropy (Sh), Conditional Entropy (CE), Permutation Entropy (PE)). Assessment of the complexity of signals in supine position indicated presence of significant differences between HUTT(+) versus HUTT(−) patients only for Conditional Entropy (CE(RRI)). Values of CE(RRI) higher than 0.7 indicate likelihood of a positive result of HUTT already at the passive phase. During tilting, in the pre-syncope phase, significant differences were found for: (SE(sBP), SE(dBP), FE(RRI), FE(sBP), FE(dBP), FE(SV), Sh(sBP), Sh(SV), CE(sBP), CE(dBP)). HUTT(+) patients demonstrated significant changes in signals' complexity more frequently than HUTT(−) patients. When comparing entropy measurements done in the supine position with those during tilting, SV assessed in HUTT(+) patients was the only parameter for which all tested measures of entropy (SE(SV), FE(SV), Sh(SV), CE(SV), PE(SV)) showed significant differences.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Entropy Measures in Analysis of Head up Tilt Test Outcome for Diagnosing Vasovagal Syncope

Buszko

Piątkowska

Koźluk

et al. 2018

Entropy

View full text Add to dashboard Cite

show abstract

“…Although this is the first study to show the influence of BPV in patients with OI, accumulating evidence suggests that increased BPV is implicated in vasovagal syncope, which is considered a specific variant of OI syndrome [1, 21]. The cardiovascular time series analysis suggested that patients with vasovagal syncope had significantly increased BPV during orthostatic challenge compared to controls [22]. Excessive BPV was accompanied by sympathetic hyperactivity and vagal withdrawal, which suggested autonomic dysregulation in response to orthostatic stress.…”

Section: Discussionmentioning

confidence: 99%

Association of blood pressure variability with orthostatic intolerance symptoms

et al. 2017

View full text Add to dashboard Cite

The short-term blood pressure variability (BPV) reflects autonomic regulatory mechanisms. However, the influence of BPV in orthostatic intolerance (OI) is unknown. Herein, we assessed BPV profiles in patients with OI and determined their association with orthostatic symptoms. In this cross-sectional study, we prospectively enrolled 126 patients presenting with OI at the Seoul National University Hospital from December 2014 to August 2016. Among them, those with other neurological diseases (n = 8) and insufficient BP measurements (n = 15) were excluded. The degree of OI symptoms were measured using the self-administered orthostatic intolerance questionnaire (OIQ). All patients underwent ambulatory BP monitoring and we calculated the standard deviation and coefficient of variation as a measure of BPV. The mean age was 48.6 years and the average of the total OIQ score was 11.6. The severe OI group had higher BPV values than the mild group, although mean BP profiles did not differ significantly. Correlation analysis demonstrated that the orthostatic symptoms were positively correlated with diastolic BPV for the total and awake periods. Multiple linear regression analysis revealed that diastolic BPV (B = 0.46, p = 0.031) and current smoking (B = 4.687, p = 0.018) were independent factors for higher OI symptom scores after adjusting for covariates. The results of the current study demonstrated that a positive correlation exists between BPV and OI symptoms. Further studies are required to confirm the present findings and understand the neural mechanisms contributing to the excessive BPV in patients with OI.

show abstract

“…Tilt-test queda ou manutenção dos valores de pressão arterial sistólica anteriores a síncope, outros documentam, no mesmo período, que houve, no espectro de potência, aumento ou diminuição na modulação da potência de baixa frequência da pressão arterial, dependente do balanço simpático sobre as arteríolas periféricas (LAGI et al, 1996;IACOVIELLO et al, 2008;HAUSENLOY et al, 2009;MEREU et al, 2013;BARBIC et al, 2015;REULECKE et al, 2016).…”

Section: Variabilidade Da Frequência Cardíaca (Vfc) Variabilidade Daunclassified

Caracterização da modulação autonômica cardiovascular nas posições supina e vertical, usando-se a manobra postural passiva, em pacientes com história clínica de síncope neurocardiogênica e indivíduos saudáveis

Leite¹

View full text Add to dashboard Cite

Orthostatic stress causes immediately increased blood pressure variability in women with vasovagal syncope

Cited by 22 publications

References 29 publications

Entropy Measures in Analysis of Head up Tilt Test Outcome for Diagnosing Vasovagal Syncope

Entropy Measures in Analysis of Head up Tilt Test Outcome for Diagnosing Vasovagal Syncope

Association of blood pressure variability with orthostatic intolerance symptoms

Caracterização da modulação autonômica cardiovascular nas posições supina e vertical, usando-se a manobra postural passiva, em pacientes com história clínica de síncope neurocardiogênica e indivíduos saudáveis

Contact Info

Product

Resources

About