Origanum majorana Essential Oil Inhalation during Neurofeedback Training Reduces Saliva Myeloperoxidase Activity at Session-1 in Bruxistic Patients

Abstract

Introduction: Bruxism affects teeth and provokes sleep alterations. We evaluated whether saliva Myeloperoxidase (MPO) activity could be reduced after 21 neurofeedback training (NO) sessions in Origanum majorana (AE) bruxistic-treated patients (n = 12 patients, 120 saliva samples). The term divergence evaluates cerebral activity, which was compared between bruxistic patients with/without this essential oil exposure during 21 NO training sessions (n = 12, n = 120 saliva samples). The nasal filter used allow us to vehiculizate this Origanum majorana essential oil in patients. MPO activity was measured in six training NO sessions (Session S1, 6, 12, 18, 21). We included a total of 104 patients and 500 saliva samples. Results: there was a fast reduction in MPO activity after NO session-1 in bruxistic patients; divergence (an index of NO training brain efficacy) is the difference in cerebral activity found between pre-training and post-training levels. Thus, Divergence can fluctuate during NO training before reaching a final calm state after many sessions (21). Repeated NO training lead to habituation in so far as cerebral activity as well as MPO activity after 21 training sessions. Origanum majorana essential oil modulates cerebral activity at certain training sessions in bruxistic patients. Stress levels were reduced on the perceived stress scores (PSS: Cohen Scale) after 21 NO sessions than for those bruxistic without NO training sessions. Conclusions: MPO activity could predict stress level in bruxistic patients and repeated NO reduced their stress level; Origanum majorana essential oil enhanced these anxiolytic effects.

Memory-Enhancing Effects of Origanum majorana Essential Oil in an Alzheimer’s Amyloid beta1-42 Rat Model: A Molecular and Behavioral Study

“…Recently, a group of researchers demonstrated that Origanum majorana essential oil (OmEO) exerted antidepressant-like effects by modulating noradrenergic, dopaminergic, and serotonergic systems [ 18 ]. Another group of researchers showed that OmEO alleviated anxiety in bruxistic patients and claimed that this essential oil might represent a safe alternative for benzodiazepine treatment [ 19 ]. Moreover, O. majorana possesses anti-inflammatory properties [ 20 ].…”

Uso domiciliar de plantas medicinais por usuários dos serviços das Unidades Básicas de Saúde do município de Toledo, Paraná

“…e sálvia (Salvia sclarea L.) promove alívio da dor provocada pela dismenorreia primária [38] . O óleo essencial de Origanum majorana aumentou o efeito ansiolítico em pacientes portadores de bruxismo [39] . Os resultados levantados por Erenler et al [40] mostraram que o extrato de O. majorana L. exibiram atividades antioxidantes significativas.…”

Role and mechanism of aromatherapy on hemodynamic parameters for patients with cardiovascular disease: A systematic review

“…Recently, the popularity of herbal remedies has increased due to their easy access, fewer complications, unique diversity of chemical structures, and biological activities (9). Medicinal plant aromas were shown to be effective in improving hemodynamic variables and treating stress and anxiety in several studies (10)(11)(12). Aromatherapy and the use of medicinal plant oils in reducing anxiety have long been considered in traditional medicine.…”