Organic thin film transistors‐based biosensors

Sun, Chenfang; Wang, Xue; Auwalu, Muhammad Aminu; Cheng, Shanshan; Hu, Wenping

doi:10.1002/eom2.12094

Cited by 65 publications

(60 citation statements)

References 104 publications

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“…[98][99][100] In the following subsections, insight into OECT and EGOFET working principles will be given, respectively. The device physics of EGOTs, their architectures, as well as a survey on the different functionalization strategies for biosensing purposes have been discussed in several reviews [101][102][103][104][105][106] and the reader can refer to them for more thorough overviews of the field.…”

Section: Electrolyte-gated Organic Electronic Transistorsmentioning

confidence: 99%

Sensing Inflammation Biomarkers with Electrolyte‐Gated Organic Electronic Transistors

Burtscher

Urbina

Diacci

et al. 2021

Adv Healthcare Materials

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An overview of cytokine biosensing is provided, with a focus on the opportunities provided by organic electronic platforms for monitoring these inflammation biomarkers which manifest at ultralow concentration levels in physiopathological conditions. Specifically, two of the field's state-of-the-art technologies-organic electrochemical transistors (OECTs) and electrolyte gated organic field effect transistors (EGOFETs)-and their use in sensing cytokines and other proteins associated with inflammation are a particular focus. The overview will include an introduction to current clinical and "gold standard" quantification techniques and their limitations in terms of cost, time, and required infrastructure. A critical review of recent progress with OECT-and EGOFET-based protein biosensors is presented, alongside a discussion onthe future of these technologies in the years and decades ahead. This is especially timely as the world grapples with limited healthcare diagnostics during the Coronavirus disease (COVID-19)pandemic where one of the worst-case scenarios for patients is the "cytokine storm." Clearly, low-cost point-of-care technologies provided by OECTs and EGOFETs can ease the global burden on healthcare systems and support professionals by providing unprecedented wealth of data that can help to monitor disease progression in real time.

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Section: Electrolyte-gated Organic Electronic Transistorsmentioning

confidence: 99%

Sensing Inflammation Biomarkers with Electrolyte‐Gated Organic Electronic Transistors

Burtscher

Urbina

Diacci

et al. 2021

Adv Healthcare Materials

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“…Despite this, OFETs are still appealing for application niches not filled by conventional electronic technologies such as selective detection of chemical compounds or sensing platforms in bioelectronics. [7] Recently, vat dyes of natural origin used traditionally for textiles, such as indigo and its derivatives, were shown to behave as semiconducting active materials in organic based OFETs. [8,9] The structural similarity to biological compounds and their potential bio-compatibility and non-toxicity, [10][11][12] suggest the use of both natural and nature-inspired dyes in biomedical applications.…”

Section: Introductionmentioning

confidence: 99%

Bulk and Surface‐Mediated Polymorphs of Bio‐Inspired Dyes Organic Semiconductors: The Role of Lattice Phonons in their Investigation

Salzillo

Giunchi

Pandolfi

et al. 2021

Israel Journal of Chemistry

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Raman spectroscopy of organic molecular materials in the low-wavenumber region gives access to lattice vibrational modes and to the wealth of information on solid state properties that these can provide. In the field of organic electronics a useful application concerns the discrimination of the crystalline forms i. e. polymorphism of the semiconductor. The capability of characterizing and identifying the polymorphs of a compound is in fact the prerequisite for an exhaustive study of the charge transport characteristics which arise from the relationship between molecular, electronic, and crystal structures. Thus, the need is felt of a noninvasive, non-destructive tool such as Raman, which probes the crystal phase by detecting the lattice modes which are sensitive even to subtle variations of the packing. Here we review the contribution of the technique to the study of organic pigments displaying promising semiconducting properties and characterized by polymorphism both in their bulk and thin film phases.

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“…In recent years, novel thin‐film materials have been used in a wide range of devices including biosensors, [ 1,2 ] photovoltaics, [ 3 ] and displays. [ 4,5 ] These material systems offer the panacea of a low cost, flexible device with a low energy input and the associated reduction in CO 2 emission during fabrication.…”

Section: Introductionmentioning

confidence: 99%

Understanding Printed Hexagonal Contacts for Large Area Solar Cells through Simulation and Experiments

et al. 2021

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Since their conception, organic electronic semiconductors have promised large area optoelectronic devices that can be mass produced at a fraction of the cost and embodied energy of devices made from traditional semiconductors. However, upscaling from small area lab‐scale fabrication techniques to large area roll‐to‐roll (R2R) production has proved a substantial challenge. At the heart of this upscaling problem is the need for low cost, reliable contacts which can be readily printed. Device performance is often limited by the contacts, in terms of charge extraction efficiency and morphological compatibility of the sequentially deposited layers. Herein, high‐speed R2R flexographic and gravure printing are combined with numerical device modeling to understand the performance of printed silver hexagonal contacts, and how contact design can affect final device performance. A strategy is presented which we dub “virtual upscaling” whereby the performance of the printed contact is virtually evaluated with an active layer material/device structure before the full device stack is printed. Through this methodology, a set of general design rules is developed which can be applied when experimentally optimizing contacts of optoelectronic devices. This approach has the potential to significantly reduce the number of design iterations and thus print runs when upscaling a structure.

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Organic thin film transistors‐based biosensors

Cited by 65 publications

References 104 publications

Sensing Inflammation Biomarkers with Electrolyte‐Gated Organic Electronic Transistors

Sensing Inflammation Biomarkers with Electrolyte‐Gated Organic Electronic Transistors

Bulk and Surface‐Mediated Polymorphs of Bio‐Inspired Dyes Organic Semiconductors: The Role of Lattice Phonons in their Investigation

Understanding Printed Hexagonal Contacts for Large Area Solar Cells through Simulation and Experiments

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