Purpose: This study explored the effect of structured teaching program on organ donation in improving knowledge and attitude among students of selected School of Jammu. Methods: This study used a Pre-experimental one group Pre-test Post test design. Sixty students were recruited using purposive sampling and they received intervention. The knowledge and attitude related to organ donation was evaluated at the baseline followed by the intervention on the next day. Chi-square and paired t test was used to evaluate the association and effectiveness of the intervention. Results: The structured teaching program was effective in improving knowledge and attitude among school students. Mean Post test knowledge score was 15.35 and mean Pre test knowledge score was found to be 7.93 with mean difference of 7.42. The computed “t” value (19.32) was found to be significant at 0.05 level of significance. Mean Post test attitude score was (39.22) and mean Pre test attitude score was (28.47) with mean difference of 10.75. The computed ”t” value (19.256) was found to be significant at 0.05 level of significance. Conclusion: The structured teaching program was effective in improving the knowledge and attitude related to organ donation among school students. Hence educational intervention should be carried out in improving the knowledge and attitude.