Orbital Metastasis of Renal Carcinoma

Ocular adnexal metastases from renal cell carcinoma

“…Review of the literature identified 44 patients[ 8 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 ] who met the inclusion criteria for this study. Table 1 summarizes the demographics and presenting characteristics.…”

“…Two patients with a locally advanced disease involving sinuses and skull base underwent orbital exenteration, either as a monotherapy (reported in 2012)[ 38 ] or followed by radiotherapy (reported in 1957). [ 13 ] Twenty-five of 42 (60%) patients had systemic treatment in addition to any local OA therapy, which included biologic agents only (11/42, 26%), chemotherapy only (3/42, 7%), radiotherapy only (1/42, 2%), surgical resection of extra-OA metastases (1/42, 2%), palliative therapy (1/42, 2%), and combination therapy in 8 out of 42 (19%). The combination therapy included radiotherapy with surgery (2/8, 25%), chemotherapy with biologic agents (2/8, 25%), radiotherapy with biologic agents (2/8, 25%), chemotherapy with radiotherapy and biologic agents (1/8, 13%), and chemotherapy with radiosurgery (1/8, 13%).…”

Ocular adnexal metastases from renal cell carcinoma

“…Review of the literature identified 44 patients[ 8 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 ] who met the inclusion criteria for this study. Table 1 summarizes the demographics and presenting characteristics.…”

“…Two patients with a locally advanced disease involving sinuses and skull base underwent orbital exenteration, either as a monotherapy (reported in 2012)[ 38 ] or followed by radiotherapy (reported in 1957). [ 13 ] Twenty-five of 42 (60%) patients had systemic treatment in addition to any local OA therapy, which included biologic agents only (11/42, 26%), chemotherapy only (3/42, 7%), radiotherapy only (1/42, 2%), surgical resection of extra-OA metastases (1/42, 2%), palliative therapy (1/42, 2%), and combination therapy in 8 out of 42 (19%). The combination therapy included radiotherapy with surgery (2/8, 25%), chemotherapy with biologic agents (2/8, 25%), radiotherapy with biologic agents (2/8, 25%), chemotherapy with radiotherapy and biologic agents (1/8, 13%), and chemotherapy with radiosurgery (1/8, 13%).…”

Ocular adnexal metastases from renal cell carcinoma

“…Review of the literature identified 44 patients[ 8 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 ] who met the inclusion criteria for this study. Table 1 summarizes the demographics and presenting characteristics.…”

“…Two patients with a locally advanced disease involving sinuses and skull base underwent orbital exenteration, either as a monotherapy (reported in 2012)[ 38 ] or followed by radiotherapy (reported in 1957). [ 13 ] Twenty-five of 42 (60%) patients had systemic treatment in addition to any local OA therapy, which included biologic agents only (11/42, 26%), chemotherapy only (3/42, 7%), radiotherapy only (1/42, 2%), surgical resection of extra-OA metastases (1/42, 2%), palliative therapy (1/42, 2%), and combination therapy in 8 out of 42 (19%). The combination therapy included radiotherapy with surgery (2/8, 25%), chemotherapy with biologic agents (2/8, 25%), radiotherapy with biologic agents (2/8, 25%), chemotherapy with radiotherapy and biologic agents (1/8, 13%), and chemotherapy with radiosurgery (1/8, 13%).…”

Ocular adnexal metastases from renal cell carcinoma

“…Review of the literature identified 44 patients[ 8 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 ] who met the inclusion criteria for this study. Table 1 summarizes the demographics and presenting characteristics.…”

“…Two patients with a locally advanced disease involving sinuses and skull base underwent orbital exenteration, either as a monotherapy (reported in 2012)[ 38 ] or followed by radiotherapy (reported in 1957). [ 13 ] Twenty-five of 42 (60%) patients had systemic treatment in addition to any local OA therapy, which included biologic agents only (11/42, 26%), chemotherapy only (3/42, 7%), radiotherapy only (1/42, 2%), surgical resection of extra-OA metastases (1/42, 2%), palliative therapy (1/42, 2%), and combination therapy in 8 out of 42 (19%). The combination therapy included radiotherapy with surgery (2/8, 25%), chemotherapy with biologic agents (2/8, 25%), radiotherapy with biologic agents (2/8, 25%), chemotherapy with radiotherapy and biologic agents (1/8, 13%), and chemotherapy with radiosurgery (1/8, 13%).…”