Orbital metastases in colorectal cancer: a case report

García-Fernández, María; Castro-Navarro, J.; Ayala, Antonio Saiz; Álvarez-Fernández, Carlos

doi:10.1016/j.oftale.2011.08.001

Cited by 6 publications

(3 citation statements)

References 3 publications

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“…Of these, 43 articles were included, five articles of potential interest could not be accessed [48][49][50][51][52] and seven articles of potential interest were published in languages other than English with no translation available. [53][54][55][56][57][58][59] Data are presented as absolute numbers as well as percentages compared to available data.…”

Section: Search Methodologymentioning

confidence: 99%

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Metastasis to the extraocular muscles: a case report, literature review and pooled data analysis

Leung

Wei

Roberts

2018

Clinical Exper Ophthalmology

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Metastasis to the extraocular muscles (EOM) is rare. The existing literature comprises only of isolated case reports therefore a summative description of these lesions is lacking. This study presents a case of bilateral rectus muscle metastasis from malignant melanoma. Furthermore a literature review and pooled data analysis is undertaken with 43 articles encompassing 77 patients and 101 eyes. Mean age was 53 years, 54% were male, 66% had unilateral involvement and 34% had bilateral involvement. The primary malignancies were melanoma (n = 17, 22%), breast (n = 15, 15%) and carcinoid (n = 11, 14%). A single muscle was involved in 56 eyes (67%) and multiple muscles in 27 eyes (33%). Lateral rectus was most commonly affected (n = 44, 53%). Presenting symptoms included restricted eye movements (n = 48, 62%), proptosis (n = 45, 58%), diplopia (n = 27, 35%) and pain (n = 18, 23%). Scattered case reports have previously made it difficult to characterise this phenomenon thus a pooled data analysis is presented.

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Section: Search Methodologymentioning

confidence: 99%

“…The search methodology identified 135 articles. Of these, 43 articles were included, five articles of potential interest could not be accessed and seven articles of potential interest were published in languages other than English with no translation available …”

Section: Literature Reviewmentioning

confidence: 99%

Metastasis to the extraocular muscles: a case report, literature review and pooled data analysis

Leung

Wei

Roberts

2018

Clinical Exper Ophthalmology

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“…CRC may lead to a variety of distance metastases including the lung, liver, peritoneum, brain, and bones [1,3,10,11]. Less common sites of metastasis secondary to CRC include the bladder, brain, adrenals, spleen, and the eye and its adnexa, whereas some isolated reports found metastatic disease in the orbit, periocular skin, retina, and choroid [4][5][6][7][12][13][14][15][16][17][18][19][20][21][22][23][24][25][26][27][28]. Carcinoma can metastasize to the uvea from any portion of the colon, although the sigmoid colon and rectum appear to be most highly represented [19,29].…”

Section: Main Textmentioning

confidence: 99%

Photodynamic Therapy of Presumed Choroidal Metastasis Secondary to Colorectal Carcinoma: Literature Review

Neto

Pulido

Melo

et al. 2020

Case Reports in Ophthalmological Medicine

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Colorectal cancer may yield metastasis to the choroid. Its management may be challenging, since there is no consensus about treatment. We describe a case of a 70-year-old male with colon cancer who complained of worsening visual acuity of his better-seeing eye to 20/40 secondary to a nonpigmented choroidal mass of medium reflectivity under the inferior temporal arcade and neurosensory foveal detachment. Besides systemic chemotherapy, local treatment with verteporfin photodynamic therapy (vPDT) was performed. After one month, visual acuity improved to 20/25 and subretinal fluid faded. In conclusion, vPDT may be a useful adjuvant treatment modality for choroidal metastasis secondary to colorectal cancer.

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Orbital metastasis mimicking internuclear ophthalmoplegia: A case report and review

Lin

Chévez-Barrios²,

Sadaka

et al. 2017

Canadian Journal of Ophthalmology

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Orbital metastases in colorectal cancer: a case report

Cited by 6 publications

References 3 publications

Metastasis to the extraocular muscles: a case report, literature review and pooled data analysis

Metastasis to the extraocular muscles: a case report, literature review and pooled data analysis

Photodynamic Therapy of Presumed Choroidal Metastasis Secondary to Colorectal Carcinoma: Literature Review

Orbital metastasis mimicking internuclear ophthalmoplegia: A case report and review

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