Vulvar cancer accounts for less than 1% of malignancies in women. Verrucous
carcinoma of the vulva is a rare histological variation, comprising less than 1%
of vulvar cancer cases. Although it is characterized as being locally invasive,
the condition is not associated with metastatic spreading. Lesions present in
the form of a verrucous, ulcerated, and bleeding tumor that can reach large
dimensions. This type of tumor can be mistaken for condylomata, both
macroscopically and microscopically. We report the case of an 81-year-old
patient with a large vulvar tumor presented for eight years, initially
considered as a Buschke-Löwenstein tumor. The patient underwent radical
vulvectomy with a V-Y advancement flap technique. This type of tumor should be
considered by clinicians dealing with condylomatous ulcerative lesions that do
not respond to the usual treatment.