Oral Use of Azithromycin for the Treatment of Acne Rosacea

Fernández-Obregón, Adolfo

doi:10.1001/archderm.140.4.489

Cited by 36 publications

(17 citation statements)

References 4 publications

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“…34 An uncontrolled study of 10 patients with moderate or severe rosacea that had responded poorly to treatment were prescribed 250 mg of azithromycin three times per week; moderate or marked improvement was observed in all patients after four weeks of therapy. 35 Oral isotretinoin in low doses has been reported to be effective in the control of rosacea that was otherwise resistant to treatment, but the ocular and cutaneous drying effects of this agent are poorly tolerated, and its potential for serious adverse effects (including teratogenic effects) contradicts its use in routine care. Topical tretinoin has been reported to be as effective as oral isotretinoin after 16 weeks of treatment 36 and may be helpful in the treatment of patients with papulopustular rosacea who also have oily skin.…”

Section: Managementmentioning

confidence: 99%

Rosacea

2005

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Section: Managementmentioning

confidence: 99%

Rosacea

2005

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“…However, there is no clear evidence that any of these antibiotics has a particular advantage in terms of higher remission rates. Azithromycin at a dose of 250 mg given 3 times a week was found to be effective and safe in the treatment of moderate to severe rosacea [79]. Tetracycline and doxycycline are commonly used in the treatment of ocular rosacea [6, 80].…”

Section: Systemic Therapymentioning

confidence: 99%

Rosacea: An Update

Buechner¹

2005

Dermatology

118

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Rosacea is a common chronic cutaneous disorder of unknown etiology which occurs most commonly in middle-aged individuals. Cutaneous manifestations include transient or persistent facial erythema, telangiectasia, edema, papules and pustules that are usually confined to the central portion of the face. The National Rosacea Society’s Expert Committee on the Classification and Staging of Rosacea identified four subtypes of rosacea: erythematotelangiectatic, papulopustular, phymatous and ocular. Recently, a standard grading system for assessing gradations of the severity of rosacea has been reported. Little is known about the cause of rosacea. Genetic, environmental, vascular, inflammatory factors and microorganisms such as Demodex folliculorum and Helicobacter pylori have been considered. Topical metronidazole and azelaic acid have been demonstrated to be effective treatments for rosacea. Severer or persistent cases may be treated with oral metronidazole, tetracyclines or isotretinoin.

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“…Azithromycin was proven to be as effective as doxycycline in a number of studies [4]. In one series, azithromycin proved beneficial after 4 weeks at 250 mg/day, for 3 days each week (Monday, Wednesday, and Friday) [30].…”

Section: Papulopustular Rosaceamentioning

confidence: 99%

Acne Rosacea

Engın¹,

Oba²,

Kutlubay³

et al. 2017

Acne and Acneiform Eruptions

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Rosacea is a common chronic inflammatory cutaneous disorder with variable presentation and severity. Disease usually occurs between the ages of 30 and 50 years. Women are more commonly affected than men. Rosacea is divided into four subtypes: erythematotelangiectatic, papulopustular, phymatous, and ocular, and one variant: lupoid or granulomatous rosacea. Erythematotelangiectatic rosacea is manifested as flushing and persistent centrofacial erythema, and papulopustular rosacea as papules and pustules in a centrofacial distribution. With disease progression, phymas consisting of sebaceous gland hypertrophy can develop. Ocular rosacea can result in blepharitis and conjunctivitis. Diagnosis is made clinically. Management of rosacea consists of protective measures such as sun protection and gentle skin care and topical and systemic treatments to suppress inflammation and erythema.

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Oral Use of Azithromycin for the Treatment of Acne Rosacea

Cited by 36 publications

References 4 publications

Rosacea

Rosacea

Rosacea: An Update

Acne Rosacea

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