Oral steroids for nasal polyps

Abstract

Randomised controlled trials and controlled clinical trials comparing oral steroids with no intervention, or placebo, or comparing doses or schedules of oral steroids in patients with multiple nasal polyps. Data collection and analysisTwo authors independently assessed study quality. We contacted study authors for additional information.

Emergence of nasal chondrosarcoma in a dog with nasal polyposis

“…The underlying etiology of nasal polyp formation in dogs – as in humans – remains unclear, although chronic inflammation may predispose to the development of nasal polyps . The optimal treatment for inflammatory nasal polyps in dogs also remains unknown, similar to the situation in human medicine, with both the potential for medical and surgical treatment options; however, regardless of the type of therapy, recurrence is considered to be common . In human medicine, the generally accepted medical practice is to attempt medical therapy as the primary treatment modality for 3 months with surgical intervention then only attempted in refractory cases .…”

Emergence of nasal chondrosarcoma in a dog with nasal polyposis

“…The underlying etiology of nasal polyp formation in dogs – as in humans – remains unclear, although chronic inflammation may predispose to the development of nasal polyps . The optimal treatment for inflammatory nasal polyps in dogs also remains unknown, similar to the situation in human medicine, with both the potential for medical and surgical treatment options; however, regardless of the type of therapy, recurrence is considered to be common . In human medicine, the generally accepted medical practice is to attempt medical therapy as the primary treatment modality for 3 months with surgical intervention then only attempted in refractory cases .…”

Management of Chronic Rhinosinusitis with Nasal Polyps and Coexisting Asthma: A Systematic Review

“…Predefined outcome measures were inspired by Cochrane reviews on the treatment of CRSwNP or CRSsNP 18–20 and categorized as sinonasal and pulmonary symptoms, nasal endoscopy and radiology, nasal function tests (peak nasal inspiratory flow, nasal nitric oxide concentration, rhinomanometry, and olfactory tests), pulmonary function tests (spirometry, peak expiratory flow [PEF], and fractional exhaled nitric oxide concentration), asthma medication intake, and adverse events.…”

Benefits and harm of systemic steroids for short- and long-term use in rhinitis and rhinosinusitis: an EAACI position paper

“…Although GCS play a key role in the treatment of various inflammatory disorders, including chronic upper airway disease, a quite extensive range of potential AE's is well‐described in literature and the chance to develop these effects seems to increase with higher dose and longer duration of treatment [8, 100–102 ].…”

Emergence of nasal chondrosarcoma in a dog with nasal polyposis

“…The underlying etiology of nasal polyp formation in dogs – as in humans – remains unclear, although chronic inflammation may predispose to the development of nasal polyps . The optimal treatment for inflammatory nasal polyps in dogs also remains unknown, similar to the situation in human medicine, with both the potential for medical and surgical treatment options; however, regardless of the type of therapy, recurrence is considered to be common . In human medicine, the generally accepted medical practice is to attempt medical therapy as the primary treatment modality for 3 months with surgical intervention then only attempted in refractory cases .…”

Management of Chronic Rhinosinusitis with Nasal Polyps and Coexisting Asthma: A Systematic Review

“…Predefined outcome measures were inspired by Cochrane reviews on the treatment of CRSwNP or CRSsNP 18–20 and categorized as sinonasal and pulmonary symptoms, nasal endoscopy and radiology, nasal function tests (peak nasal inspiratory flow, nasal nitric oxide concentration, rhinomanometry, and olfactory tests), pulmonary function tests (spirometry, peak expiratory flow [PEF], and fractional exhaled nitric oxide concentration), asthma medication intake, and adverse events.…”

Benefits and harm of systemic steroids for short- and long-term use in rhinitis and rhinosinusitis: an EAACI position paper

“…Although GCS play a key role in the treatment of various inflammatory disorders, including chronic upper airway disease, a quite extensive range of potential AE's is well‐described in literature and the chance to develop these effects seems to increase with higher dose and longer duration of treatment [8, 100–102 ].…”

Emergence of nasal chondrosarcoma in a dog with nasal polyposis

“…The underlying etiology of nasal polyp formation in dogs – as in humans – remains unclear, although chronic inflammation may predispose to the development of nasal polyps . The optimal treatment for inflammatory nasal polyps in dogs also remains unknown, similar to the situation in human medicine, with both the potential for medical and surgical treatment options; however, regardless of the type of therapy, recurrence is considered to be common . In human medicine, the generally accepted medical practice is to attempt medical therapy as the primary treatment modality for 3 months with surgical intervention then only attempted in refractory cases .…”

Management of Chronic Rhinosinusitis with Nasal Polyps and Coexisting Asthma: A Systematic Review

“…Predefined outcome measures were inspired by Cochrane reviews on the treatment of CRSwNP or CRSsNP 18–20 and categorized as sinonasal and pulmonary symptoms, nasal endoscopy and radiology, nasal function tests (peak nasal inspiratory flow, nasal nitric oxide concentration, rhinomanometry, and olfactory tests), pulmonary function tests (spirometry, peak expiratory flow [PEF], and fractional exhaled nitric oxide concentration), asthma medication intake, and adverse events.…”

Benefits and harm of systemic steroids for short- and long-term use in rhinitis and rhinosinusitis: an EAACI position paper

“…Although GCS play a key role in the treatment of various inflammatory disorders, including chronic upper airway disease, a quite extensive range of potential AE's is well‐described in literature and the chance to develop these effects seems to increase with higher dose and longer duration of treatment [8, 100–102 ].…”