Oral naltrexone maintenance treatment for opioid dependence

The role of brain creatine in behavioral health conditions

“…For example, bupropion was found in some studies to reduce cravings but not in others ( 79 , 80 ). Similarly, naltrexone has been shown to modify MA cravings, possibly via endogenous opioid pathways ( 81 ); however, evidence does not currently support its efficacy in promoting abstinence or reducing relapse rates ( 82 ). Other medications such as vigabatrin, ondansetron, topiramate, and gabapentin are under investigation, but their efficacy for MUD has not yet been established ( 83 ).…”

The role of brain creatine in behavioral health conditions

“…For example, bupropion was found in some studies to reduce cravings but not in others ( 79 , 80 ). Similarly, naltrexone has been shown to modify MA cravings, possibly via endogenous opioid pathways ( 81 ); however, evidence does not currently support its efficacy in promoting abstinence or reducing relapse rates ( 82 ). Other medications such as vigabatrin, ondansetron, topiramate, and gabapentin are under investigation, but their efficacy for MUD has not yet been established ( 83 ).…”

Cost-Effectiveness of Injectable Extended-Release Naltrexone Compared with Methadone Maintenance and Buprenorphine Maintenance Treatment for Opioid Dependence

“…We also excluded the once-daily oral formulation of naltrexone prescribed, which has been found to be less effective than either MMT or BMT. 17 For all 3 treatments, our model assumed flexible dosing of each medication in accordance with best clinical practice. [18][19][20] The Markov model used daily time cycles to simulate health outcomes and expenditures under alternative treatment regimens over a 168-day (approximately 6-month) horizon.…”

“…We also excluded the once-daily oral formulation of naltrexone prescribed, which has been found to be less effective than either MMT or BMT. 17 For all 3 treatments, our model assumed flexible dosing of each medication in accordance with best clinical practice. 18 – 20…”

Pilot Testing of an Online Training for Criminal Justice Professionals on Medication-Assisted Treatment

“…Johnson et al, 2000;R. E. Johnson, Jaffe, & Fudala, 1992;Kakko et al, 2007;Kakko, Svanborg, Kreek, & Heilig, 2003;Magura et al, 2009;Mattick, Kimber, Breen, & Davoli, 2008;Mello & Mendelson, 1980), and naltrexone (Alkermes, Inc., 2010;Comer et al, 2006;Cornish et al, 1997;Krupitsky & Blokhina, 2010;Krupitsky et al, 2011;Kunøe et al, 2009;Lobmaier, Kunøe, Gossop, Katevoll, & Waal, 2010;Minozzi et al, 2006). Despite evidence supporting the effectiveness of medicationassisted treatment (MAT) for individuals who are addicted, these medications remain underutilized (Institute of Medicine, 1998Medicine, , 2006.…”

The role of brain creatine in behavioral health conditions

“…For example, bupropion was found in some studies to reduce cravings but not in others ( 79 , 80 ). Similarly, naltrexone has been shown to modify MA cravings, possibly via endogenous opioid pathways ( 81 ); however, evidence does not currently support its efficacy in promoting abstinence or reducing relapse rates ( 82 ). Other medications such as vigabatrin, ondansetron, topiramate, and gabapentin are under investigation, but their efficacy for MUD has not yet been established ( 83 ).…”

Cost-Effectiveness of Injectable Extended-Release Naltrexone Compared with Methadone Maintenance and Buprenorphine Maintenance Treatment for Opioid Dependence

“…We also excluded the once-daily oral formulation of naltrexone prescribed, which has been found to be less effective than either MMT or BMT. 17 For all 3 treatments, our model assumed flexible dosing of each medication in accordance with best clinical practice. [18][19][20] The Markov model used daily time cycles to simulate health outcomes and expenditures under alternative treatment regimens over a 168-day (approximately 6-month) horizon.…”

“…We also excluded the once-daily oral formulation of naltrexone prescribed, which has been found to be less effective than either MMT or BMT. 17 For all 3 treatments, our model assumed flexible dosing of each medication in accordance with best clinical practice. 18 – 20…”

Pilot Testing of an Online Training for Criminal Justice Professionals on Medication-Assisted Treatment

“…Johnson et al, 2000;R. E. Johnson, Jaffe, & Fudala, 1992;Kakko et al, 2007;Kakko, Svanborg, Kreek, & Heilig, 2003;Magura et al, 2009;Mattick, Kimber, Breen, & Davoli, 2008;Mello & Mendelson, 1980), and naltrexone (Alkermes, Inc., 2010;Comer et al, 2006;Cornish et al, 1997;Krupitsky & Blokhina, 2010;Krupitsky et al, 2011;Kunøe et al, 2009;Lobmaier, Kunøe, Gossop, Katevoll, & Waal, 2010;Minozzi et al, 2006). Despite evidence supporting the effectiveness of medicationassisted treatment (MAT) for individuals who are addicted, these medications remain underutilized (Institute of Medicine, 1998Medicine, , 2006.…”

The role of brain creatine in behavioral health conditions

“…For example, bupropion was found in some studies to reduce cravings but not in others ( 79 , 80 ). Similarly, naltrexone has been shown to modify MA cravings, possibly via endogenous opioid pathways ( 81 ); however, evidence does not currently support its efficacy in promoting abstinence or reducing relapse rates ( 82 ). Other medications such as vigabatrin, ondansetron, topiramate, and gabapentin are under investigation, but their efficacy for MUD has not yet been established ( 83 ).…”

Cost-Effectiveness of Injectable Extended-Release Naltrexone Compared with Methadone Maintenance and Buprenorphine Maintenance Treatment for Opioid Dependence

“…We also excluded the once-daily oral formulation of naltrexone prescribed, which has been found to be less effective than either MMT or BMT. 17 For all 3 treatments, our model assumed flexible dosing of each medication in accordance with best clinical practice. [18][19][20] The Markov model used daily time cycles to simulate health outcomes and expenditures under alternative treatment regimens over a 168-day (approximately 6-month) horizon.…”

“…We also excluded the once-daily oral formulation of naltrexone prescribed, which has been found to be less effective than either MMT or BMT. 17 For all 3 treatments, our model assumed flexible dosing of each medication in accordance with best clinical practice. 18 – 20…”

Pilot Testing of an Online Training for Criminal Justice Professionals on Medication-Assisted Treatment

“…Johnson et al, 2000;R. E. Johnson, Jaffe, & Fudala, 1992;Kakko et al, 2007;Kakko, Svanborg, Kreek, & Heilig, 2003;Magura et al, 2009;Mattick, Kimber, Breen, & Davoli, 2008;Mello & Mendelson, 1980), and naltrexone (Alkermes, Inc., 2010;Comer et al, 2006;Cornish et al, 1997;Krupitsky & Blokhina, 2010;Krupitsky et al, 2011;Kunøe et al, 2009;Lobmaier, Kunøe, Gossop, Katevoll, & Waal, 2010;Minozzi et al, 2006). Despite evidence supporting the effectiveness of medicationassisted treatment (MAT) for individuals who are addicted, these medications remain underutilized (Institute of Medicine, 1998Medicine, , 2006.…”