Oral <i>Candida</i> carriage, quantification, and species characterization in oral submucous fibrosis patients and healthy individuals

Kamat, Mamata; Vanaki, Shrinivas S.; Puranik, Rudrayya S; Puranik, Surekha R; Kaur, Ramanpreet

doi:10.1111/j.2041-1626.2011.00078.x

Cited by 14 publications

(12 citation statements)

References 12 publications

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“…The prevalence of Candida species in OSMF subjects was slightly lower than that observed in Sri Lankan patients (63.6%) [18]. Conversely our study had a higher prevalence than few other studies [13,15,19,22].…”

Section: Discussioncontrasting

confidence: 84%

Oral Candidal Carriage Among Patients with Oral Potential Malignant Disorders: A Case-Control Study

Sankari

Mahalakshmi

2019

Pesqui. bras. odontopediatria clín. integr.

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Objective: To determine the prevalence of Candida species in the saliva of patients with clinically suspected oral potentially malignant disorders (OPMD) and healthy cohorts. Material and Methods: Unstimulated saliva was collected from patients with OPMD (n=100) and age and sex matched healthy subjects (n=170). The samples were inoculated onto Sabouraud Dextrose Agar and incubated for a week. The colonies of the isolates were enumerated using a colony counter. The isolates were identified using standard phenotypic methods. The significance of oral candidal carriage was calculated using Independent T test. Odds and Risk ratio was calculated using Pearson's Chi-square test. Results: Oral candida carriage was present in 51% of patients with OPMD while healthy cohorts had a prevalence of 20.6%. A good statistical significance was observed for the prevalence of oral candidal carriage for patients with OPMD in comparison to healthy cohorts (p=0.013). Significant Odds and risk ratio was observed for the prevalence of Candida species among OPMD. Majority of the isolates in both groups were C. albicans. Colony forming units were high among patients with OPMD. Conclusion: A significant association of oral candidal carriage to oral potentially malignant disorders in comparison to healthy cohorts was observed. Candidal species may be potent risk factor for transition of OPMD to oral Squamous Cell Carcinoma.

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Section: Discussioncontrasting

confidence: 84%

Oral Candidal Carriage Among Patients with Oral Potential Malignant Disorders: A Case-Control Study

Sankari

Mahalakshmi

2019

Pesqui. bras. odontopediatria clín. integr.

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“…C. tropicalis is also reported to be the predominant isolate in India as per geographic variation. [36][37][38][39][40][41][42] This observation is unique to the present study as we could not find similar observations in literature in OSF patients. Similar divergence in mycotic flora has been reported in few populations which can be attributed to the influence of nutritional, social, environmental factors, and oral hygiene practices.…”

Section: Discussioncontrasting

confidence: 54%

Oral candidal carriage and species identification among betel quid chewers and oral submucous fibrosis patients

Somashekhar¹,

Kamath²,

Ramanna³

2016

JCRI

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Background:The Candida species are saprophytic component of the normal oral microbiota. The disequilibrium in the homeostasis between Candida, host immune system and normal oral bacterial flora promotes a Candida carriage. Aim of the Study: The present study was done to assess oral candidal carriage and species identification among healthy subjects, betel quid chewing (BQC), and oral submucous fibrosis (OSF) patients using CHROMagar® media. Materials and Methods: Oral swabs collected from the reservoirs of Candida species (buccal mucosa and tongue) in study groups using sterile cotton swabs were inoculated on Sabouraud's dextrose agar candidal medium and CHROMagar® Candida agar medium consecutively. Determination of Candida species was done based on morphology characteristics and pigment produced. The results were statistically analyzed using Chi-square test. Results: Candida carriage was more in samples of buccal mucosa followed by the tongue. Candida albicans was the major isolate in both healthy subjects and BQC but with greater frequency in BQC. Candida tropicalis was the major isolate in OSF patients predominantly in buccal mucosa followed by the tongue. Conclusion: C. tropicalis, a non-C. albicans species, was the major isolate in OSF. This unique finding implicates an immunological change of oral environment brought about by BQC and OSF.

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“…70 Patients with OSMF can have an elevated level of candidal infection, and the number of colony forming units may increase with longer duration of the betel-quid chewing habit. 71 Patients with OLP also have higher rates of candidal infection compared with healthy individuals, with a shift toward a species other than C. albicans. 72 Patients with chronic mucocutaneous candidiasis, particularly those with autoimmune polyendocrinopathy candidal ectodermal dystrophy may be at risk of OSCC and esophageal malignancy.…”

Section: Uncommon Risk Factors Candidal Infectionmentioning

confidence: 99%

Risk factors and etiopathogenesis of potentially premalignant oral epithelial lesions

Porter

Gueiros

Leão

et al. 2018

Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology

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Potentially malignant oral mucosal disease has some ability to give rise to malignancy of the oral epithelium, that is, oral squamous cell carcinoma (OSCC). The present article provides a succinct review of the possible or probable causes of potentially premalignant oral epithelial lesions. There is a focus upon studies that examined the causes or etiologic associations with clinically likely or histopathologically detectable oral epithelial dysplasia.

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Oral Candida carriage, quantification, and species characterization in oral submucous fibrosis patients and healthy individuals

Cited by 14 publications

References 12 publications

Oral Candidal Carriage Among Patients with Oral Potential Malignant Disorders: A Case-Control Study

Oral Candidal Carriage Among Patients with Oral Potential Malignant Disorders: A Case-Control Study

Oral candidal carriage and species identification among betel quid chewers and oral submucous fibrosis patients

Risk factors and etiopathogenesis of potentially premalignant oral epithelial lesions

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