Oral Florid Papillomatosis

Samitz, M. H.; Weinberg, Richard A.

doi:10.1001/archderm.1963.01590160070013

Cited by 21 publications

(2 citation statements)

References 3 publications

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“…Aus den 14 uns zugäng lichen Kasuistiken [1, 8-13, 15 ,17-19] Behandlungsversuche mit Podophyllin [3,7,10,13,19], Guanidin [II], Antibiotika und Kortikosteroiden [7], Trichloressigsäure und Vitamin-A [3] sowie Immunisierung mit einer Vakzine aus Tumorgewebe [19] blieben ebenso erfolglos wie die Röntgentherapie [7,11,19], Der Anfangserfolg einer Aminopterin-Behandlung [13] konnte von D omonkos [3] nicht bestätigt werden. Die günstigsten Resultate, zumindest im Sinne einer PalliativTherapie, verspricht Methotrexat [2, 7, 9, 10, eigener Fall], Die Prognose des Leidens ist fragwürdig.…”

Section: Diskussionunclassified

Zum Krankheitsbild der sogenannten «oral florid papillomatosis» (Papillomatosis mucosae oris carcinoides)

Richter¹,

Engel²,

Jacobi³

1972

Dermatology

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Clinical and histological features, treatment and course of an ‘oral florid papillomatosis’ (OFP) observed in a 72-year-old woman are described. The discussion of all details published on OFP so far yields the following results: (1) men and middle-aged people as well as older persons are more highly to be affected by OFP; (2) even extremely large lesions still show criterias of the benign nature of OFP; (3) there is a strong tendency of recurrence; (4) methotrexate seems to give the best results in treating OFP; (5) development into malignant growth is possible, and (6) instead of the English name of ‘oral florid papillomatosis’, the name of ‘papillomatosis mucosae oris carcinoides’ is suggested.

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Section: Diskussionunclassified

Zum Krankheitsbild der sogenannten «oral florid papillomatosis» (Papillomatosis mucosae oris carcinoides)

Richter¹,

Engel²,

Jacobi³

1972

Dermatology

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“…Malignant conversion and development of squamous-cell carcinoma has been reported [31]. However, cases without malignant transformation have also been described [25,33]. Synonymously different terms such as papillomatosis mucosae carcinoides, verrucous hyperplasia and verrucous leukoplakia have been suggested [26,28,35].…”

Section: Introductionmentioning

confidence: 99%

Malignant conversion of florid oral and labial papillomatosis during topical immunotherapy with imiquimod

Wenzel

Saka

Zimmermann

et al. 2003

Medical Microbiology and Immunology

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We report a case of a 61-year-old woman suffering from florid oral papillomatosis with a squamous-cell cancer of the floor of the mouth, which was removed by scalpel surgery combined with a radical neck dissection in 1996. Between 1996 and 2000 several histologically benign papillomatous lesions of mouth and lips were removed with laser and electrosurgery. However, the lesions recurred. In July 2000 hyperkeratotic, wart-like lesions were present at the lower and upper lips and at the right angle of the mouth and the adjacent oral mucosa. Overnight treatment with a topical 5% imiquimod cream on a Monday-Wednesday-Friday schedule was initiated. However, due to severe irritation and pain the application had to be reduced to 4 h per night, three times a week, followed by a therapy-free interval of 2 weeks. Despite this treatment consisting of four cycles of 3 weeks (1 week treatment and 2 weeks pause), the lesions increased markedly in size. A biopsy taken from the tumorous lesion from the right angle of the mouth proved to be a squamous-cell carcinoma. The tumors of the labial and oral mucosal sites as well as the right submandibular lymph nodes were removed by wide scalpel excision. The lips were reconstructed by plastic surgery. 24 months after surgical intervention no recurrence nor metastasis to lymph nodes or distal sites were observed.

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Floride orale Papillomatose (Papillomatosis mucosae carcinoides)

Wolff¹,

Tappeiner²

1973

Vorträge Des VII. Fortbildungskurses Der Dermatologischen Klinik Und Poliklinik Der Universität München in Verbindung Mit Dem V

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Oral Florid Papillomatosis

Cited by 21 publications

References 3 publications

Zum Krankheitsbild der sogenannten «oral florid papillomatosis» (Papillomatosis mucosae oris carcinoides)

Zum Krankheitsbild der sogenannten «oral florid papillomatosis» (Papillomatosis mucosae oris carcinoides)

Malignant conversion of florid oral and labial papillomatosis during topical immunotherapy with imiquimod

Floride orale Papillomatose (Papillomatosis mucosae carcinoides)

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