2001
DOI: 10.1001/archderm.137.9.1208
|View full text |Cite
|
Sign up to set email alerts
|

Oral Corticosteroid Use Is Effective for Cutaneous Hemangiomas

Abstract: To determine the efficacy of systemic corticosteroid therapy in treating enlarging, problematic cutaneous hemangiomas and to assess the relationship of dose to response and adverse effects. Design: A quantitative systematic literature review was performed and inclusion and exclusion criteria were applied. Setting: Patients were treated in primary care, referral centers, and institutional practices. Most patients were ambulatory, although some required hospitalization. Patients: Inclusion criteria were original… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
2

Citation Types

4
201
0
10

Year Published

2004
2004
2015
2015

Publication Types

Select...
9

Relationship

0
9

Authors

Journals

citations
Cited by 319 publications
(215 citation statements)
references
References 21 publications
(25 reference statements)
4
201
0
10
Order By: Relevance
“…1 Until recently, corticosteroids had been the first-line treatment for life-or function-threatening infantile hemangiomas, with other treatment options being vincristine and interferon alpha. [2][3][4][5][6] However, these therapies have multiple side effects, some of which are serious. [7][8][9] In a recent case series, 10 propranolol was used to treat the obstructive hypertrophic myocardiopathy caused by corticosteroid therapy for an infantile hemangioma.…”
mentioning
confidence: 99%
“…1 Until recently, corticosteroids had been the first-line treatment for life-or function-threatening infantile hemangiomas, with other treatment options being vincristine and interferon alpha. [2][3][4][5][6] However, these therapies have multiple side effects, some of which are serious. [7][8][9] In a recent case series, 10 propranolol was used to treat the obstructive hypertrophic myocardiopathy caused by corticosteroid therapy for an infantile hemangioma.…”
mentioning
confidence: 99%
“…Until recently, the mainstay of treatment for infantile hemangiomas was corticosteroids in various forms, including topical, intralesional, and oral formulations, the most common being oral prednisolone. 12 Only in complicated or refractory hemangioma cases have other treatment modalities been considered, such as chemotherapeutic agents (vincristine, interferon-alpha), laser therapy, surgery or a combination of these, and, most recently, propranolol. Each treatment option has limited therapeutic benefit, with its own side effects and risks.…”
Section: Discussionmentioning
confidence: 99%
“…Oral corticosteroids are the therapy of choice for hemangiomas when there is a risk of complications or a potential for disfigurement. 27 Dutra (2003) reported systemic clinical treatment in 21.9% of patients and clinical treatment followed by surgery in 20.7% of patients. 26 The use of intralesional corticosteroids for hemangiomas is controversial because of the risk of side effects.…”
Section: Discussionmentioning
confidence: 99%