Oral and gastrointestinal manifestations of epidermolysis bullosa

Extracutaneous manifestations and complications of inherited epidermolysis bullosa

“…Specific complications may be seen in different sites within the gut, including esophageal blistering, strictures, and web formation (almost exclusively in DEB), gastroesophageal reflux disease (GERD), and constipation. [41][42][43][44][45] The main GI complications of EB are summarized in Table IV.…”

Epidermolysis Bullosa - A Report Of Two Cases

“…Almost in all patients fragile and hemorrhagic bullae develop at the junction of soft and hard palates (26). Dysphagia was reported to arise in the 15 per cent of patients (4,8). Although scars, intraoral and extraoral milia have reportedly been seen, these findings are not frequently observed in JEB (13,17).…”

“…Epidermolysis Bullosa (EB) is a group of rare dermal diseases producing blister spontaneously or after minor trauma, characterized by vesicular disorders of skin and mucous membranes (1)(2)(3)(4)(5)(6)(7)(8)(9). The disease may have autosomal dominant and recessive inheritance or may be acquired thereafter (1,3,9,10).…”

Esophageal manifestations of dermatologic disease

“…Additionally, some patients develop oral scarring, preventing full extension of the mandible and making intubation difficult. In selected patients, esophagectomy with colonic interposition has been successful, although in a review of 246 cases, none were reported to require surgery [3].…”