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Cited by 276 publications
(167 citation statements)
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References 41 publications
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“…This technique has been successful in improving local control 3, 4. In recent years, more highly conformal techniques have been used such as the use of mini‐beams, intensity modulated RT (IMRT) and simultaneously integrated boost, leading to improvements in three‐dimensional (3D) dose distributions 5, 6, 7. However, highly conformal techniques will only be of maximum benefit if patient setup errors can be minimised.…”
Section: Introductionmentioning
confidence: 99%
“…This technique has been successful in improving local control 3, 4. In recent years, more highly conformal techniques have been used such as the use of mini‐beams, intensity modulated RT (IMRT) and simultaneously integrated boost, leading to improvements in three‐dimensional (3D) dose distributions 5, 6, 7. However, highly conformal techniques will only be of maximum benefit if patient setup errors can be minimised.…”
Section: Introductionmentioning
confidence: 99%
“…Vicini et al reported the first clinical use of breast IMRT and noted a low occurrence of acute adverse effects on the skin in 2002 8. Another study presented the results of a matched‐pair analysis of patients who had received either breast IMRT or standard RT 9.…”
Section: Discussionmentioning
confidence: 99%
“…IMRT is more advanced than conventional techniques, and the equipment consists of a variable aperture to shape dose distributions around targets; these distributions cannot be achieved using conventional equipment. Research showed that potentially more suitable dose distributions in the clinical target volume (CTV) of the breast, a lower incidence of acute skin toxicity, and lower doses to normal lung or heart tissues were associated with IMRT than with the standard technique; in addition, the cosmetic results after IMRT use were excellent 8. Moreover, a prospective randomized trial comparing standard RT and IMRT reported that the breast appearance changed more visibly with standard RT than with IMRT in 233 patients with breast cancer 9…”
Section: Introductionmentioning
confidence: 99%
“…To represent ‘coldness' of the tumor (lack of coverage), 100‐V95 was chosen since V95 (i.e., PTV volume receiving 95% of prescription dose or more) has been widely used as a metric for coverage 15 , 16 . Similarly, V110 was calculated for representing the ‘hotness', as used for measuring dose homogeneity in previous studies 15 , 17 . Lastly, V95‐V110 was calculated to provide a composite metric accounting for both hotness and coldness of the tumor volume.…”
Section: Methodsmentioning
confidence: 99%