Optimized Deep Convolutional Neural Network for the Prediction of Breast Cancer Recurrence

Abstract

With more than 2.1 million new cases of diagnosis each year, breast cancer is considered to be the most prevalent women disease. Within 10 years, nearly 30% patients who got cured at early-stages experienced cancer recurrence. Recurrence is a crucial aspect of breast cancer behaviour that is inseparably linked to mortality. Despite its importance, the significant proportion of breast cancer datasets rarely include it, which makes research into its prediction more challenging. It is still difficult to predict who will experience a recurrence and who won't, which has implications for the treatment that goes along with it. Clinicians treating breast cancer may be able to avoid ineffective overtreatment if Artificial Intelligence (AI) methods are developed that can forecast the likelihood of breast cancer recurrence. This work proposes a novel automatic breast cancer recurrence classification and prediction system incorporating novel Deep Convolutional Neural Network (DCNN) algorithm. The proposed DCNN model is deployed on Wisconsin Breast Cancer dataset for further evaluation. The role of AI in forecasting recurrence is examined in this work. The experimental results were analysed for various combination of train and validation dataset. The accuracy, precision, recall and F1-score for the proposed DCNN was calculated as 97.63 %, 98.57 %, 96.84 %, 97.89 % respectively.