Optimization extraction, characterization and antioxidant activities of pectic polysaccharide from tangerine peels

Chen, Ruizhan; Jin, Chenguang; Tong, Zhigang; Lü, Juan; Tan, Li; Tian, Li; Chang, Qing-Quan

doi:10.1016/j.carbpol.2015.09.036

Cited by 95 publications

(41 citation statements)

References 38 publications

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“…Thus, these absorption characteristics proved that carboxymethylation occurred in the polysaccharides molecules. The current results are consistent with other observations reported in the carboxymethyl derivatives of pectic polysaccharides (Chen et al ., ) and Psyllium arabinoxylan (Bhatia & Ahuja, ).…”

Section: Resultsmentioning

confidence: 99%

Carboxymethylation of corn bran polysaccharide and its bioactive property

Shang

et al. 2017

Int J of Food Sci Tech

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Summary Corn bran polysaccharides were extracted using an ultrasonic‐assisted method with a yield of 33.50% and then carboxymethylated. The occurrence of modification was confirmed using Fourier transform infrared spectral analysis. The surface of polysaccharide particles became loosened following the carboxymethylation. The effect of sodium hydroxide concentration, reaction temperature, and the reaction time on the degree of substitution was investigated, and the relationship among the substitution degree, total phenolic content and antioxidant activity were studied. With sodium hydroxide concentration of 6.0 mol L−1, keeping the reaction temperature of 60 °C and reaction time of 5.0 h, the modified polysaccharides possessed the highest degree of substitution and antioxidant activity. Cell culture model indicated that the carboxymethylated polysaccharide significantly inhibited the proliferation of A549 and HepG‐2 cells, and these antitumour characteristics may be associated with the elevated expression of CASP3, CASP8, CASP9, and p53, as well as the significantly decreased expression of Bcl‐2 and iNOS genes. The excellent antioxidant capacity and strong antitumour activity of these polysaccharides might provide a potential application as a naturally functional ingredient.

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Section: Resultsmentioning

confidence: 99%

Carboxymethylation of corn bran polysaccharide and its bioactive property

Shang

et al. 2017

Int J of Food Sci Tech

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“…Hydroxyl radicals, generated by the reaction of Fe‐EDTA complex with H 2 O 2 in phosphate buffer, are harmful to the body through reacting with biological molecules such as amino acid and DNA . Figure shows the • OH scavenging activity of lactose, hydrophobic 6‐amino‐lactose (C), and 6‐amino‐lactose at various concentrations.…”

Section: Resultsmentioning

confidence: 99%

Synthesis of Novel Amino Lactose and Evaluation of Its Antioxidant Property

Feng

et al. 2018

Starch Stärke

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In order to improve the bioactivity of lactose, a novel lactose derivative is designed and synthesized by introducing an amino group to the C‐6 of lactose. The in vitro antioxidant activities of synthesized lactose derivatives are assessed. It shows better scavenging activity against hydrogen peroxide (IC50 < 0.1 mg mL−1), hydroxyl radicals (IC50 0.55 mg mL−1), and DPPH radicals (IC50 0.37 mg mL−1) than lactose. Based on this data, it is reasonable to propose that the introduction of amino group through chemical modification is significant to enhance the free antioxidant activity of lactose. This derivatization strategy might provide an effective tool to broaden utilization of lactose.

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“…The hydroxyl‐radical is the most reactive oxygen species and can damage adjacent biomolecules such as amino acid or DNA, resulting in aging, cancer, and several degenerative diseases . Figure showed the scavenging activity against hydroxyl‐radical of starch and aminopyridinium acetyl starch derivatives at five different concentrations, including 0.1, 0.2, 0.4, 0.8, and 1.6 mg/mL.…”

Section: Resultsmentioning

confidence: 99%

“…Superoxide can damage cells and DNA resulting to various diseases . As a highly poisonous living free radical, it could be generated by numerous biological and photochemical reactions .…”

Section: Resultsmentioning

confidence: 99%

Synthesis of aminopyridinium‐grafted starch derivatives and evaluation of their antioxidant property

et al. 2017

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In order to improve the bioactivity of starch, novel starch derivatives were developed including 2-(2-aminopyridinium)acetyl starch (2APASC), 2-(3-aminopyridinium)acetyl starch (3APASC), 2-(4-aminopyridinium)acetyl starch (4APASC), 2-(2,3-diaminopyridinium)acetyl starch (2,3DAPASC), 2-(2,6-diaminopyridinium)acetyl starch (2,6DAPASC), and 2-(3,4-diaminopyridinium)acetyl starch (3,4DAPASC). The in vitro antioxidant capacities against hydroxyl-radical, DPPH-radical, and superoxide-radical for all synthesized starch derivatives were evaluated using free radicals scavenging assays. The results showed that the scavenging effect of starch derivatives bearing aminopyridinium groups was better than starch. Especially, 2,3DAPASC and 2,6DAPASC could scavenge hydroxyl-radicals completely at 0.4 mg/mL. Moreover, the antioxidant property of synthesized starch derivatives was affected by the different positions and the number of amino groups on pyridinium rings. Because the aminopyridinium acetyl starch derivatives could be synthesized conveniently and also possessed significantly strong antioxidant activity, this synthetic strategy might provide an effective tool to broaden further utilization of starch.

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Optimization extraction, characterization and antioxidant activities of pectic polysaccharide from tangerine peels

Cited by 95 publications

References 38 publications

Carboxymethylation of corn bran polysaccharide and its bioactive property

Carboxymethylation of corn bran polysaccharide and its bioactive property

Synthesis of Novel Amino Lactose and Evaluation of Its Antioxidant Property

Synthesis of aminopyridinium‐grafted starch derivatives and evaluation of their antioxidant property

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