2016
DOI: 10.1161/circulationaha.116.024393
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Abstract: Background: No randomized study has investigated the value of optical coherence tomography (OCT) in optimizing the results of percutaneous coronary intervention (PCI) for non–ST-segment elevation acute coronary syndromes. Methods: We conducted a multicenter, randomized study involving 240 patients with non–ST-segment elevation acute coronary syndromes to compare OCT-guided PCI (use of OCT pre- and post-PCI; OCT-guided group) to fluoroscopy-guided PCI (a… Show more

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Cited by 250 publications
(110 citation statements)
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“…Observational or retrospective data obtained with use of the more recently developed OCT are even less conclusive than those obtained over the years with IVUS guidance. 1 The study reported here by Meneveau et al 2 is an important milestone in the journey to accumulating sufficient global evidence to support the role of OCT-guidance eventually during complex PCI and to extend the Practice Guidelines recommendations supporting its use.…”
mentioning
confidence: 78%
“…Observational or retrospective data obtained with use of the more recently developed OCT are even less conclusive than those obtained over the years with IVUS guidance. 1 The study reported here by Meneveau et al 2 is an important milestone in the journey to accumulating sufficient global evidence to support the role of OCT-guidance eventually during complex PCI and to extend the Practice Guidelines recommendations supporting its use.…”
mentioning
confidence: 78%
“…Meneveau et al showed that the incidence of acute kidney injury, defined as an absolute increase in serum creatinine of !0.5 mg/dL from baseline, was only 1.6% in both OCT-and angio-guided PCI in cases of ACS, although greater contrast was observed in OCT-guided PCI (190 versus 120 mL, P < 0.0001). 21) In the OPINION trial, no contrast-induced nephropathy, defined as an increase in serum creatinine level of !0.5 mg/ dL or a relative increase of !25% over baseline value within 72 hours, was observed in both OFDI-and IVUSguided PCI. 7) Because these studies excluded patients with CKD (e.g., estimated glomerular filtration rate < 30 mL/ minute/1.73 m 2 or serum creatinine level > 1.5 mg/dL in the OPINION study), the impact of OCT-guided PCI on the incidence of acute kidney injury in daily practice was unclear.…”
Section: Discussionmentioning
confidence: 99%
“…Recently, many studies have begun to comprehensively test OCT's potential role outside of research as a common tool for the cardiac catheterization lab. Studies have indicated that OCT-guided percutaneous coronary intervention is associated with improved outcome relative to conventional procedures guided by angiography alone [99,100]. Studies have shown that abnormalities following stenting were frequently found by OCT and that irregular tissue protrusion between stent struts and small minimal stent area were independent predictors of outcome [101,102].…”
Section: Clinical Studiesmentioning
confidence: 99%