volume 85, issue 5, P539-543 2009
DOI: 10.1038/clpt.2008.297
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Abstract: This review presents an update on the development of ophthalmic drug delivery systems (Table 1), as well as regulatory aspects of product development. This review is based on full papers and published patents as of November 2008. PersPectiveLocal ocular delivery provides unique therapeutic opportunities and challenges. Drugs can be delivered directly to the anterior portions of the eye in relatively simple formulations, providing, de facto, an enhanced therapeutic index. The eye is an immuneprivileged site, 1…

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