Open tension-free Lichtenstein repair of inguinal hernia: use of fibrin glue versus sutures for mesh fixation

Negro, Paolo; Burzotta, Francesco; Brescia, Antonio; Buonanno, G. M.; Campanelli, G.; Canonico, S; Cavalli, Marta; Corrado, G.; Coscarella, G; Lorenzo, Nicola Di; Falletto, Ezio; Fei, Landino; Francucci, Marsilio; Baldelli, C. Fronticelli; Gaspari, Achille; Gianetta, Ezio; Marvaso, A; Palumbo, Piergaspare; Pellegrino, N.; Piazzai, R.; Salvi, Pier Federico; Stabilini, Cesare; Zanghì, G

doi:10.1007/s10029-010-0706-8

Cited by 73 publications

(52 citation statements)

References 14 publications

(12 reference statements)

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“…Several studies in various hernia repairs both open and laparoscopic using fibrin glue have shown promising results. 8,9 This is further authenticated by our study.…”

Section: Mechanism Of Actionsupporting

confidence: 68%

A prospective study of laparoscopic repair of inguinal hernia by intraperitoneal onlay mesh technique using fibrin glue

2016

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“…Several studies in various hernia repairs both open and laparoscopic using fibrin glue have shown promising results. 8,9 This is further authenticated by our study.…”

Section: Mechanism Of Actionsupporting

confidence: 68%

A prospective study of laparoscopic repair of inguinal hernia by intraperitoneal onlay mesh technique using fibrin glue

2016

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“…Mesh biomaterial in the form of lightweight mesh and heavyweight mesh has also been reported to be involved in the aetiology and pathogenesis of chronic groin pain [12][13][14][15]. Mesh fixation techniques potentially contributing to the development of chronic groin pain include the use of staples, tackers, sutures, autologous glues and synthetic glues [16][17][18][19][20][21]. Various measures to counteract the issues related to CGP and less predominantly related to hernia recurrence are being explored continuously.…”

Section: Introductionmentioning

confidence: 99%

Laparoscopic Versus Open Preperitoneal Mesh Repair of Inguinal Hernia: an Integrated Systematic Review and Meta-analysis of Published Randomized Controlled Trials

2015

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The objective of this article is to systematically analyse the randomized, controlled trials comparing open (OPPR) versus laparoscopic (LPPR) preperitoneal mesh repair of inguinal hernia. Randomized, controlled trials comparing OPPR versus LPPR of inguinal hernia were analysed systematically using RevMan®, and combined outcomes were expressed as odds ratio (OR) and standardized mean difference (SMD). Ten randomized trials evaluating 1286 patients were retrieved from the electronic databases. There were 606 patients in the OPPR repair group and 680 patients in the LPPR group. There was significant heterogeneity among trials (p < 0.0001). Therefore, in the random effects model, LPPR was associated with longer operative time and relatively lesser postoperative pain in the case of the trans-abdominal preperitoneal approach. Statistically, both OPPR and LPPR were equivalent in terms of developing chronic groin pain, recurrence and postoperative complications. OPPR of inguinal hernia is associated with shorter operative time and comparable with LPPR (both total extraperitoneal and trans-abdominal preperitoneal approaches) in terms of risk of chronic groin pain, recurrence and complications.

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“…The pain perceptions were significantly higher in the suture group as compared to the fibrin glue group (p value <0.001). The study by Negro et al [15] also showed that the mean pain score was significantly lower in the fibrin glue group than the suture group (2.5 vs. 3.2, p<0.001) and fibrin glue group patients also experienced less intense pain (0.6 vs. 1.2; p=0.001).…”

Section: Discussionmentioning

confidence: 86%

A Prospective Randomized Study Comparing Fibrin Glue Versus Prolene Suture for Mesh Fixation in Lichtenstein Inguinal Hernia Repair

et al. 2015

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The aim of this study is to assess the advantages of fibrin glue over Prolene suture in fixation of the mesh in open inguinal hernia repair. Sixty-four cases of inguinal hernia underwent hernia repair by the Lichtenstein method in the department of surgery in PGIMER & Dr. RML Hospital, New Delhi. The patients were randomized prospectively into group A (fibrin glue group) and group B (Prolene suture group). In group A, fibrin glue was used for mesh fixation, and in group B, Prolene suture was used for mesh fixation. The mean age of patients in group A was 44.5 years and that of group B patients was 44.2 years. There was a significant difference in the duration of surgery, with the mean duration in fibrin glue group being 30.6 min and that of the suture group was 43.3 min. The mean visual analogue pain score of postoperative pain at 1, 6, 12, and 24 h was significantly higher in the suture group than in the fibrin glue group (p<0.001). The mean total dose of analgesia in ampoules of tramadol was significantly less in the fibrin glue group (1.56 ampoules) than that in the suture group (4.125 ampoules) with p=0.000. At the end of the first month, 25 % of subjects in the suture group presented with mild groin pain (p value=0.0048). At the end of the second and third month, 22 % (p 68 value=0.0048) and 12.5 % (p value=0.1132) of subjects respectively presented with mild groin pain in the suture group. The present study demonstrates that the use of fibrin glue in place of Prolene suture for mesh fixation in open inguinal hernia repair can help decreasing the time required for surgery, reduce the intensity of postoperative pain, shorten the duration of hospital stay, and prevent the incidence of chronic groin pain.

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Open tension-free Lichtenstein repair of inguinal hernia: use of fibrin glue versus sutures for mesh fixation

Abstract: Tissucol fibrin glue for mesh fixation in the Lichtenstein repair of inguinal hernia shows advantages over sutures, including lower incidence of complications such as pain, numbness, and discomfort, and should be considered as a first-line option for mesh fixation in hernioplasty.

Cited by 73 publications

References 14 publications

A prospective study of laparoscopic repair of inguinal hernia by intraperitoneal onlay mesh technique using fibrin glue

A prospective study of laparoscopic repair of inguinal hernia by intraperitoneal onlay mesh technique using fibrin glue

Laparoscopic Versus Open Preperitoneal Mesh Repair of Inguinal Hernia: an Integrated Systematic Review and Meta-analysis of Published Randomized Controlled Trials

A Prospective Randomized Study Comparing Fibrin Glue Versus Prolene Suture for Mesh Fixation in Lichtenstein Inguinal Hernia Repair

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