Opacification of Scleral-Sutured Akreos Ao60 Intraocular Lens After Vitrectomy With Gas Tamponade: Case Series

Kalevar, Ananda; Dollin, Michael; Gupta, R. Rishi

doi:10.1097/icb.0000000000000634

Cited by 40 publications

(28 citation statements)

References 8 publications

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“…Several reports described the opacification occurred after intravitreal gas injection during pars plana vitrectomy (PPV), the surgical procedure performed for treating diseases of the posterior segment of the eye [ 6 , 23 , 32 , 36 , 68 , 69 , 70 , 71 , 72 ]. The typical appearance of the opacification in most cases was similar to that occurring after DSAEK/DMEK [ 6 , 17 , 23 , 32 , 36 , 62 , 68 , 69 , 70 , 71 , 72 ]. Because the opacification appears mainly on the anterior surface of the IOL, although gas is injected into the vitreous, it is presumed that gas is likely to migrate into the anterior chamber through damaged zonular fibers [ 70 ].…”

Section: Resultsmentioning

confidence: 99%

“…Opacification of hydrophilic acrylic IOLs following intraocular gas injection has been described not only after intracameral injection of air or gas. Several reports described the opacification occurred after intravitreal gas injection during pars plana vitrectomy (PPV), the surgical procedure performed for treating diseases of the posterior segment of the eye [6,23,32,36,[68][69][70][71][72]. The typical appearance of the opacification in most cases was similar to that occurring after DSAEK/DMEK [6,17,23,32,36,62,[68][69][70][71][72].…”

Section: Sedimentation Mechanismmentioning

confidence: 99%

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Physicochemical Analysis of Sediments Formed on the Surface of Hydrophilic Intraocular Lens after Descemet’s Stripping Endothelial Keratoplasty

et al. 2020

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An intraocular lens (IOL) is a synthetic, artificial lens placed inside the eye that replaces a natural lens that is surgically removed, usually as part of cataract surgery. The opacification of the artificial lens can be related to the formation of the sediments on its surface and could seriously impair vision. The physicochemical analysis was performed on an explanted hydrophilic IOL and compared to the unused one, considered as a reference IOL. The studies were carried out using surface sensitive techniques, which can contribute to a better understanding of the sedimentation process on hydrophilic IOLs’ surfaces. The microscopic studies allowed us to determine the morphology of sediments observed on explanted IOL. The photoelectron spectroscopy measurements revealed the presence of organic and inorganic compounds at the lens surface. Mass spectroscopy measurements confirmed the chemical composition of deposits and allowed for chemical imaging of the IOL surface. Applied techniques allowed to obtain a new set of information approximating the origin of the sediments’ formation on the surface of the hydrophilic IOLs after Descemet’s stripping endothelial keratoplasty.

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Section: Resultsmentioning

confidence: 99%

Section: Sedimentation Mechanismmentioning

confidence: 99%

Physicochemical Analysis of Sediments Formed on the Surface of Hydrophilic Intraocular Lens after Descemet’s Stripping Endothelial Keratoplasty

et al. 2020

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“…In relation to PPV, either combined with phacoemulsification or alone, it is postulated that intracameral gas could contribute to the calcification of the surface of the IOL . Although the exact mechanism of calcification is under investigation, one hypothesis is that local damage to the hydrophilic IOL surface due to direct contact with air/gas at the exposed area may lead to Ca/P deposition from the aqueous humour .…”

Section: Discussionmentioning

confidence: 99%

“…Of the 45 articles, five did not fulfil the inclusion criteria and were excluded from further analysis. The remaining included articles numbered 40 and were analysed using the Pierson tool …”

Section: Methodsmentioning

confidence: 99%

Systematic review of potential causes of intraocular lens opacification

Fernández

Sánchez‐García

Rodríguez‐Vallejo³

et al. 2019

Clinical Exper Ophthalmology

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Intraocular lens (IOL) opacification is an infrequent complication of cataract sur-gery. Surface analysis has demonstrated that the opacification of IOLs is related to calcium or phosphate precipitation on or within the lenses, but the associated mechanisms are unknown, and the scientific literature is heterogeneous and limited to case series and retrospective studies. The purpose of this systematic review was to analyse the most frequent conditions associated with opacification of IOLs reported by studies. A search was carried out using the PubMed MEDLINE, Web of Science and Scopus databases. The quality of the studies selected was evaluated using the Pierson tool. The search provided a total of 811 articles, of which 39 were selected following the inclusion and exclusion criteria. The most common opacified lenses were hydrophilic IOLs according to our analysis. The mean time of appearance of lens opacification was 14.93 ± 17.82 months. The most frequent conditions associated with opacification of the IOLs were Descemet Stripping with Automated Endothelial Keratoplasty (DSAEK/DSEK) and diabetes mellitus (DM), followed by pars plana vitrectomy (PPV), blood hypertension (HT), and glaucoma.Concerning the quality analysis, the mean score was 7.00 ± 1.43 (scoring range from 0 to 10), indicating an acceptable quality of the case reports and retrospective studies. In conclusion, DSAEK/DSEK, DM, PPV, glaucoma and hypertension are conditions with potential risk of IOL opacification after cataract surgery, especially when implanting hydrophilic acrylic IOLs. K E Y W O R D Sacrylic IOL, cataract surgery, intraocular lens, IOL explantation, IOL opacification

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“…Bausch & Lomb Akreos AO60 hydrophilic acrylic lens contains 4 eyelets allowing 4 point fixation. However, these lenses undergo calcification and opacify when in contact with intraocular gas or air [26]. Given that aphakic patients often have coincident retinal pathology and might be at increased risk for retinal detachment repair this might be an important consideration when deciding on the optimal lens and fixation technique.…”

Section: Scleral-fixated Intraocular Lensmentioning

confidence: 99%

Secondary Intraocular Lens

Manoharan¹,

Prasad²

2020

Intraocular Lens

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Secondary intraocular lens (IOL) implantation has evolved over the past few decades. Several new techniques, lens options, and materials now exist. Careful patient selection is important to determine the optimal secondary IOL technique. Intraocular lens placement in the capsular bag is the most ideal followed by sulcus placement. However, the best option when no capsular support exists in an aphakic patient remains unclear. Surgeons should be aware of contraindications for each technique; however, there are several situations where anterior chamber intraocular lens (ACIOL), scleral-fixated intraocular lens (SFIOL), and iris fixation can all be used. In those cases, surgeon familiarity and comfort with the secondary IOL technique can determine the type of surgery performed.

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Opacification of Scleral-Sutured Akreos Ao60 Intraocular Lens After Vitrectomy With Gas Tamponade: Case Series

Abstract: Although still an excellent option for the management of surgical aphakia in the absence of capsular support, caution should be taken when using a hydrophilic secondary intraocular lens, such as Akreos AO60, during vitreoretinal surgery if gas is required.

Cited by 40 publications

References 8 publications

Physicochemical Analysis of Sediments Formed on the Surface of Hydrophilic Intraocular Lens after Descemet’s Stripping Endothelial Keratoplasty

Physicochemical Analysis of Sediments Formed on the Surface of Hydrophilic Intraocular Lens after Descemet’s Stripping Endothelial Keratoplasty

Systematic review of potential causes of intraocular lens opacification

Secondary Intraocular Lens

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