Ontogeny of energy and carbohydrate utilisation of the precocial avian embryo and hatchling

Foye, O. T.; Ferket, P. R.; Uni, Zehava

doi:10.3184/147020607x296033

Cited by 10 publications

(6 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Gluconeogenesis becomes the critical source of glucose. In the avian embryo, the primary gluconeogenic precursors are amino acids, derived from the amnion and muscles [21,22]. Many researches have demonstrated that supplementation with exogenous nutrients via IOF technology could improve energy reserves during late incubation of embryos and neonatal broilers [1].…”

Section: Discussionmentioning

confidence: 99%

In ovo feeding of creatine pyruvate alters energy metabolism in muscle of embryos and post-hatch broilers

Yang¹,

Zhao²,

Li³

et al. 2019

Asian-Australas J Anim Sci

View full text Add to dashboard Cite

Objective This study was conducted to investigate the effects of in ovo feeding (IOF) of creatine pyruvate (CrPyr) on the energy metabolism in thigh muscle of embryos and neonatal broilers. Methods A total of 960 eggs were randomly assigned to three treatments: i) non-injected control group, ii) saline group injected with 0.6 mL of physiological saline (0.75%), and iii) CrPyr group injected with 0.6 mL of physiological saline (0.75%) containing 12 mg CrPyr/egg on 17.5 d of incubation. After hatching, 120 male chicks (close to the average body weight of the pooled group) in each group were randomly assigned to eight replications. The feeding experiment lasted 7 days. Results The results showed that IOF of CrPyr increased glucose concentrations in the thigh muscle of broilers on 2 d after injection (p<0.05). Compared with the control and saline groups, the concentration of creatine in CrPyr group was increased on 2 d after injection and the day of hatch (p<0.05). Moreover, IOF of CrPyr increased the creatine kinase activity at hatch and increased the activities of hexokinase and pyruvate kinase on 2 d after injection and the day of hatch (p<0.05). Chicks in CrPyr group showed higher mRNA expressions of glucose transporter 3 (GLUT3) and GLUT8 on the day of hatch (p<0.05). Conclusion These results demonstrated that IOF of CrPyr was beneficial to enhance muscle energy reserves of embryos and hatchlings.

show abstract

Section: Discussionmentioning

confidence: 99%

In ovo feeding of creatine pyruvate alters energy metabolism in muscle of embryos and post-hatch broilers

Yang¹,

Zhao²,

Li³

et al. 2019

Asian-Australas J Anim Sci

View full text Add to dashboard Cite

show abstract

“…Plasma glucose concentrations increase just before the hatching process starts, probably to ensure normal activity of the central nervous system [18] and to emerge successfully from the eggshell. This increase in glucose is a result of the mobilization of hepatic glycogen [12], [18], [19], [20]. Because glucose is hardly available in the egg at the start of incubation (<1%) [9], glycogen stores are built up during the incubation period in the heart, liver, muscle, and yolk sac membrane [19], [20], [21], [22].…”

Section: Introductionmentioning

confidence: 99%

High Environmental Temperature Increases Glucose Requirement in the Developing Chicken Embryo

Molenaar¹,

Borne

Hazejager

et al. 2013

PLoS ONE

View full text Add to dashboard Cite

Environmental conditions during the perinatal period influence metabolic and developmental processes in mammals and avian species, which could impact pre- and postnatal survival and development. The current study investigated the effect of eggshell temperature (EST) on glucose metabolism in broiler chicken embryos. Broiler eggs were incubated at a high (38.9°C) or normal (37.8°C) EST from day 10.5 of incubation onward and were injected with a bolus of [U-13C]glucose in the chorio-allantoic fluid at day 17.5 of incubation. After [U-13C]glucose administration, 13C enrichment was determined in intermediate pools and end-products of glucose metabolism. Oxidation of labeled glucose occurred for approximately 3 days after injection. Glucose oxidation was higher in the high than in the normal EST treatment from day 17.6 until 17.8 of incubation. The overall recovery of 13CO2 tended to be 4.7% higher in the high than in the normal EST treatment. An increase in EST (38.9°C vs 37.8°C) increased 13C enrichment in plasma lactate at day 17.8 of incubation and 13C in hepatic glycogen at day 18.8 of incubation. Furthermore, high compared to normal EST resulted in a lower yolk-free body mass at day 20.9 (−2.74 g) and 21.7 (−3.81 g) of incubation, a lower hepatic glycogen concentration at day 18.2 (−4.37 mg/g) and 18.8 (−4.59 mg/g) of incubation, and a higher plasma uric acid concentration (+2.8 mg/mL/+43%) at day 21.6 of incubation. These results indicate that the glucose oxidation pattern is relatively slow, but the intensity increased consistently with an increase in developmental stage of the embryo. High environmental temperatures in the perinatal period of chicken embryos increased glucose oxidation and decreased hepatic glycogen prior to the hatching process. This may limit glucose availability for successful hatching and could impact body development, probably by increased gluconeogenesis from glucogenic amino acids to allow anaerobic glycolysis.

show abstract

“…Our present study indicated that IOF of 1% Arg increased YFBW at hatch in comparison to conventional hatchlings. The carbohydrate metabolism of avian embryos and neonates is dominated by hepatic gluconeogenesis ( De Oliveira et al., 2008 ), and the gluconeogenic pathway is extremely active throughout embryonic development ( Foye et al., 2007 ). In previous studies, Arg administration has been shown to boost glucose synthesis in the liver, which correlates with enhanced glucose 6-phosphatase activity at hatch ( Tangara et al., 2010 ; Yu et al., 2018a ).…”

Section: Discussionmentioning

confidence: 99%

Effects of low eggshell temperatures during incubation, in ovo feeding of L-arginine, and post-hatch dietary guanidinoacetic acid on hatching traits, performance, and physiological responses of broilers reared at low ambient temperature

et al. 2022

View full text Add to dashboard Cite

This study aimed to investigate the effect of eggshell temperature ( ET ) manipulations during incubation, in ovo feeding ( IOF ) of arginine, and post-hatch dietary supplementation with guanidinoacetic acid ( GAA ) on hatching traits and subsequent growth and physiological performance of hatched broiler chicks reared under subnormal temperature. In experiment 1, from d 8 of incubation onward, a total of 2,160 hatching eggs were randomly arranged in a 2 × 3 factorial design, in which the eggs were exposed to 2 ET (37.8°C or periodically low ET), and 3 IOF treatments (noninjected, diluent-injected, and 1% arginine solution-injected). In experiment 2, a total of 576 one-day-old male broiler chicks from 2 temperature conditions and 2 IOF treatment groups (noninjected and Arg-injected) were reared for 42 d with or without GAA supplementation in a 2 × 2 × 2 factorial design. Each treatment had 6 replicates with 12 birds each. A subnormal ambient temperature (17°C) was applied from 15 d onward to induce ascites. Results from experiment 1 showed a 2-way interaction between ET and IOF for embryonic mortality rate during 19 to 21 d of incubation and residual yolk weight at hatch ( P < 0.05). A periodically low ET significantly increased yolk free body mass, first-grade chicks, and relative heart weight than an ET of 37.8°C. In the second experiment, overall average daily gain ( ADG ) was increased, but feed conversion ratio ( FCR ), ascites mortality, and serum thyroid hormones and corticosterone were reduced in the low ET group ( P < 0.05). There were also IOF × GAA interactions for ADG and FCR ( P < 0.05). IOF of arginine or dietary GAA increased serum nitric oxide concentration and jejunal villus height, but decreased ascites mortality ( P < 0.05). In conclusion, a periodically low ET accompanied by IOF of arginine during incubation and posthatch dietary supplementation with GAA could be a useful strategy for improving the chick quality at hatch and subsequent improvements in post-hatch performance and ascites indices in cold-stressed broilers.

show abstract

Ontogeny of energy and carbohydrate utilisation of the precocial avian embryo and hatchling

Cited by 10 publications

References 0 publications

In ovo feeding of creatine pyruvate alters energy metabolism in muscle of embryos and post-hatch broilers

In ovo feeding of creatine pyruvate alters energy metabolism in muscle of embryos and post-hatch broilers

High Environmental Temperature Increases Glucose Requirement in the Developing Chicken Embryo

Effects of low eggshell temperatures during incubation, in ovo feeding of L-arginine, and post-hatch dietary guanidinoacetic acid on hatching traits, performance, and physiological responses of broilers reared at low ambient temperature

Contact Info

Product

Resources

About