“…Also, three‐component coupling reaction catalyzed by ZnCl 2, TBBDA, TsOH and Boron sulfuric acid provides the synthesis of various 4,5‐disubstituted pyrimidine derivatives via one‐pot reaction from acetophenones, triethylorthoformate, and ammonium acetate. In view of the green chemistry, we tried in this work to substitute harmful substrate by magnetic nano‐Fe 3 O 4 based on pyridine as a novel nanocatalyst which contains surface high density Br 3 − in the synthesis of pyrimidines, so, we propose a new route for the synthesis of pyrimidines, from one‐pot reaction of triethoxymethane, various ketones and ammonium acetate using nano‐magnetic functional pyridiniunm‐tribromide (TBP‐SCMNPs), as a novel catalyst and choline chloride/urea mixture as a deep eutectic solvent (Scheme ).…”