On the Intravenous, Not the Intraspinal, Use of Arsphenamin in Syphilis of the Nervous System

100 Years of JAMA Neurology and the Journey Back to the Beginning

“…neurological manifestations of and new therapies for syphilis 5,6 to attempts to treat what was likely schizophrenia using injections of sodium chloride, 7 as well as detailed descriptions of wartime spinal cord and peripheral nerve injuries. 8,9 The first volume's issues were groundbreaking and robust for the time, with great relevance to the practicing physician-certainly an impressive accomplishment for such a fledgling journal.…”

“…Articles advancing treatments of “so-called ‘shell shock’” and “war neuroses” sit comfortably next to a piece on the histogenesis of multiple sclerosis . In the issues that followed over the next few months, observations ranged from the neurological manifestations of and new therapies for syphilis to attempts to treat what was likely schizophrenia using injections of sodium chloride, as well as detailed descriptions of wartime spinal cord and peripheral nerve injuries . The first volume’s issues were groundbreaking and robust for the time, with great relevance to the practicing physician—certainly an impressive accomplishment for such a fledgling journal.…”

100 Years of JAMA Neurology and the Journey Back to the Beginning

“…neurological manifestations of and new therapies for syphilis 5,6 to attempts to treat what was likely schizophrenia using injections of sodium chloride, 7 as well as detailed descriptions of wartime spinal cord and peripheral nerve injuries. 8,9 The first volume's issues were groundbreaking and robust for the time, with great relevance to the practicing physician-certainly an impressive accomplishment for such a fledgling journal.…”

“…Articles advancing treatments of “so-called ‘shell shock’” and “war neuroses” sit comfortably next to a piece on the histogenesis of multiple sclerosis . In the issues that followed over the next few months, observations ranged from the neurological manifestations of and new therapies for syphilis to attempts to treat what was likely schizophrenia using injections of sodium chloride, as well as detailed descriptions of wartime spinal cord and peripheral nerve injuries . The first volume’s issues were groundbreaking and robust for the time, with great relevance to the practicing physician—certainly an impressive accomplishment for such a fledgling journal.…”

Intraspinal Treatment in Neurosyphilis

“…In another case the fluid remains strongly positive. CONCLUSIONS 1. The Swift-Ellis intraspinal method of treatment of syphilis of the central nervous system is superior to intensive intravenous treat¬ ment alone.…”

100 Years of JAMA Neurology and the Journey Back to the Beginning

“…neurological manifestations of and new therapies for syphilis 5,6 to attempts to treat what was likely schizophrenia using injections of sodium chloride, 7 as well as detailed descriptions of wartime spinal cord and peripheral nerve injuries. 8,9 The first volume's issues were groundbreaking and robust for the time, with great relevance to the practicing physician-certainly an impressive accomplishment for such a fledgling journal.…”

“…Articles advancing treatments of “so-called ‘shell shock’” and “war neuroses” sit comfortably next to a piece on the histogenesis of multiple sclerosis . In the issues that followed over the next few months, observations ranged from the neurological manifestations of and new therapies for syphilis to attempts to treat what was likely schizophrenia using injections of sodium chloride, as well as detailed descriptions of wartime spinal cord and peripheral nerve injuries . The first volume’s issues were groundbreaking and robust for the time, with great relevance to the practicing physician—certainly an impressive accomplishment for such a fledgling journal.…”

Intraspinal Treatment in Neurosyphilis

“…In another case the fluid remains strongly positive. CONCLUSIONS 1. The Swift-Ellis intraspinal method of treatment of syphilis of the central nervous system is superior to intensive intravenous treat¬ ment alone.…”

100 Years of JAMA Neurology and the Journey Back to the Beginning

“…neurological manifestations of and new therapies for syphilis 5,6 to attempts to treat what was likely schizophrenia using injections of sodium chloride, 7 as well as detailed descriptions of wartime spinal cord and peripheral nerve injuries. 8,9 The first volume's issues were groundbreaking and robust for the time, with great relevance to the practicing physician-certainly an impressive accomplishment for such a fledgling journal.…”

“…Articles advancing treatments of “so-called ‘shell shock’” and “war neuroses” sit comfortably next to a piece on the histogenesis of multiple sclerosis . In the issues that followed over the next few months, observations ranged from the neurological manifestations of and new therapies for syphilis to attempts to treat what was likely schizophrenia using injections of sodium chloride, as well as detailed descriptions of wartime spinal cord and peripheral nerve injuries . The first volume’s issues were groundbreaking and robust for the time, with great relevance to the practicing physician—certainly an impressive accomplishment for such a fledgling journal.…”

Intraspinal Treatment in Neurosyphilis

“…In another case the fluid remains strongly positive. CONCLUSIONS 1. The Swift-Ellis intraspinal method of treatment of syphilis of the central nervous system is superior to intensive intravenous treat¬ ment alone.…”