1999
DOI: 10.1211/0022357991773258
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Abstract: Secoiridoides (oleuropein and derivatives), one of the major classes of polyphenol contained in olives and olive oil, have recently been shown to inhibit or delay the rate of growth of a range of bacteria and microfungi but there are no data in the literature concerning the possible employment of these secoiridoides as antimicrobial agents against pathogenic bacteria in man. In this study five ATCC standard bacterial strains (Haemophilus influenzae ATCC 9006, Moraxella catarrhalis ATCC 8176, Salmonella typhi A… Show more

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Cited by 438 publications
(327 citation statements)
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“…Digestion with trypsin yielded the four expected A␤ fragments: [1][2][3][4][5], [6 -16], [17][18][19][20][21][22][23][24][25][26][27][28], and [29 -40] following cleavage after arginine (R) or lysine (K) residues (Table 2), as well as partially cleaved fragments ( Table 3). The soft ESI ionization also enabled the detection of noncovalent interactions between sequential and nonsequential fragments.…”
Section: Resultsmentioning
confidence: 99%
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“…Digestion with trypsin yielded the four expected A␤ fragments: [1][2][3][4][5], [6 -16], [17][18][19][20][21][22][23][24][25][26][27][28], and [29 -40] following cleavage after arginine (R) or lysine (K) residues (Table 2), as well as partially cleaved fragments ( Table 3). The soft ESI ionization also enabled the detection of noncovalent interactions between sequential and nonsequential fragments.…”
Section: Resultsmentioning
confidence: 99%
“…Noncovalent interactions of peptide fragments with OE, added before digestion, were detected for the [17][18][19][20][21][22][23][24][25][26][27][28] fragment of A␤ (Figure 2) and the partially cleaved peptide fragments [6 -28] and [6 -40]. In addition, noncovalent complexes of OE with the [5][6][7][8][9][10][11][12][13][14][15][16][17][18][19] fragment, derived from the chymotryptic activity of the enzyme, was also detected.…”
Section: Resultsmentioning
confidence: 99%
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