On the Familial Incidence of Amyotrophic Lateral Sclerosis

Clinical Aspects of Familial Forms of Frontotemporal Dementia Associated with Parkinsonism

“…Patients with this condition exhibit signs of parkinsonism, MND, and dementia (Uitti et al 1995). However, similar cases with complex phenotype were reported earlier as for example by Sercle and Kovarik, Yvonneau et al, Alter and Schaumann, Gilbert et al, and Eisen et al (Sercle and Kovarik 1963; Yvonneau et al 1971; Alter and Schaumann 1976; Gilbert et al 1988; Eisen and Calne 1992). More recently, additional cases were studied by Mochizuki et al, Kuzuhara and Kokubo, Imamura et al, Portera-Cailliau et al, Schweitzer et al, McCluskey et al, and Gilbert et al (Mochizuki et al 2004; Kuzuhara and Kokubo 2005; Imamura et al 2007; Portera-Cailliau et al 2007; McCluskey et al 2009; Schweitzer et al 2009; Gilbert et al 2010).…”

Clinical Aspects of Familial Forms of Frontotemporal Dementia Associated with Parkinsonism

“…Patients with this condition exhibit signs of parkinsonism, MND, and dementia (Uitti et al 1995). However, similar cases with complex phenotype were reported earlier as for example by Sercle and Kovarik, Yvonneau et al, Alter and Schaumann, Gilbert et al, and Eisen et al (Sercle and Kovarik 1963; Yvonneau et al 1971; Alter and Schaumann 1976; Gilbert et al 1988; Eisen and Calne 1992). More recently, additional cases were studied by Mochizuki et al, Kuzuhara and Kokubo, Imamura et al, Portera-Cailliau et al, Schweitzer et al, McCluskey et al, and Gilbert et al (Mochizuki et al 2004; Kuzuhara and Kokubo 2005; Imamura et al 2007; Portera-Cailliau et al 2007; McCluskey et al 2009; Schweitzer et al 2009; Gilbert et al 2010).…”

Familial Amyotrophic Lateral Sclerosis, 1850-1989: A Statistical Analysis of the World Literature

“…73 Several other families fell into this broad category of exclusion. 74 " 77 The second type consisted of those families in which ALS was well documented in the proband yet other fami-ly members suffered from PBP, PMA 7879 or from such minor changes as hyporeflexia. 80 Occasional reports were encountered where the proband clearly suffered from ALS, yet the key related case suffered from an unrelated illness mistakenly described as ALS.…”

Incidence and Risk Factors of Motor Neuron Disease in the Venice and Padua Districts of Italy, 1972–1979

“…5-10% of the cases that occur sporadically are familial, probably trans mitted as an autosomal-dominant trait with variable penetrance [4,5]. Symptoms in most patients develop during the second half of life, but onset occurs between the 5th and 7th decades.…”

Clinical Aspects of Familial Forms of Frontotemporal Dementia Associated with Parkinsonism

“…Patients with this condition exhibit signs of parkinsonism, MND, and dementia (Uitti et al 1995). However, similar cases with complex phenotype were reported earlier as for example by Sercle and Kovarik, Yvonneau et al, Alter and Schaumann, Gilbert et al, and Eisen et al (Sercle and Kovarik 1963; Yvonneau et al 1971; Alter and Schaumann 1976; Gilbert et al 1988; Eisen and Calne 1992). More recently, additional cases were studied by Mochizuki et al, Kuzuhara and Kokubo, Imamura et al, Portera-Cailliau et al, Schweitzer et al, McCluskey et al, and Gilbert et al (Mochizuki et al 2004; Kuzuhara and Kokubo 2005; Imamura et al 2007; Portera-Cailliau et al 2007; McCluskey et al 2009; Schweitzer et al 2009; Gilbert et al 2010).…”

Familial Amyotrophic Lateral Sclerosis, 1850-1989: A Statistical Analysis of the World Literature

“…73 Several other families fell into this broad category of exclusion. 74 " 77 The second type consisted of those families in which ALS was well documented in the proband yet other fami-ly members suffered from PBP, PMA 7879 or from such minor changes as hyporeflexia. 80 Occasional reports were encountered where the proband clearly suffered from ALS, yet the key related case suffered from an unrelated illness mistakenly described as ALS.…”

Incidence and Risk Factors of Motor Neuron Disease in the Venice and Padua Districts of Italy, 1972–1979

“…5-10% of the cases that occur sporadically are familial, probably trans mitted as an autosomal-dominant trait with variable penetrance [4,5]. Symptoms in most patients develop during the second half of life, but onset occurs between the 5th and 7th decades.…”

Clinical Aspects of Familial Forms of Frontotemporal Dementia Associated with Parkinsonism

“…Patients with this condition exhibit signs of parkinsonism, MND, and dementia (Uitti et al 1995). However, similar cases with complex phenotype were reported earlier as for example by Sercle and Kovarik, Yvonneau et al, Alter and Schaumann, Gilbert et al, and Eisen et al (Sercle and Kovarik 1963; Yvonneau et al 1971; Alter and Schaumann 1976; Gilbert et al 1988; Eisen and Calne 1992). More recently, additional cases were studied by Mochizuki et al, Kuzuhara and Kokubo, Imamura et al, Portera-Cailliau et al, Schweitzer et al, McCluskey et al, and Gilbert et al (Mochizuki et al 2004; Kuzuhara and Kokubo 2005; Imamura et al 2007; Portera-Cailliau et al 2007; McCluskey et al 2009; Schweitzer et al 2009; Gilbert et al 2010).…”

Familial Amyotrophic Lateral Sclerosis, 1850-1989: A Statistical Analysis of the World Literature

“…73 Several other families fell into this broad category of exclusion. 74 " 77 The second type consisted of those families in which ALS was well documented in the proband yet other fami-ly members suffered from PBP, PMA 7879 or from such minor changes as hyporeflexia. 80 Occasional reports were encountered where the proband clearly suffered from ALS, yet the key related case suffered from an unrelated illness mistakenly described as ALS.…”

Incidence and Risk Factors of Motor Neuron Disease in the Venice and Padua Districts of Italy, 1972–1979

“…5-10% of the cases that occur sporadically are familial, probably trans mitted as an autosomal-dominant trait with variable penetrance [4,5]. Symptoms in most patients develop during the second half of life, but onset occurs between the 5th and 7th decades.…”