2020
DOI: 10.1101/2020.09.24.20200766
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Abstract: Background: Brazil became the epicenter of the COVID-19 epidemic in a brief period of a few months after the first officially registered case. The knowledge of the epidemiological/clinical profile and the risk factors of Brazilian COVID-19 patients can assist in the decision making of physicians in the implementation of early and most appropriate measures for poor prognosis patients. However, these reports are missing. Here we present a comprehensive study that addresses this demand. Methods: This data-driven … Show more

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Cited by 14 publications
(18 citation statements)
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References 33 publications
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“…Finally, we observed that the profile of COVID-19 patients with breakthrough infection is similar to that of unvaccinated COVID-19 patients who were hospitalized when Brazil did not have vaccines (31), corroborating a study that also found such a result (9). In our study, the main similarities between the profiles were older age, male gender, cough, dyspnoea, respiratory distress, low blood oxygen saturation, and comorbidities such as heart disease, diabetes, obesity, kidney disease, neuropathy and pneumopathy.…”
Section: Discussionsupporting
confidence: 84%
“…Finally, we observed that the profile of COVID-19 patients with breakthrough infection is similar to that of unvaccinated COVID-19 patients who were hospitalized when Brazil did not have vaccines (31), corroborating a study that also found such a result (9). In our study, the main similarities between the profiles were older age, male gender, cough, dyspnoea, respiratory distress, low blood oxygen saturation, and comorbidities such as heart disease, diabetes, obesity, kidney disease, neuropathy and pneumopathy.…”
Section: Discussionsupporting
confidence: 84%
“…Moreover, similar to our results, older age, shortness of breath and the kidney disease were also estimated to be risk factors associated with the mortality from COVID-19. A more general study conducted by Souza et al [24] accounting for 208,969 hospitalized patients in Brazil, shows that the mortality rate in this country is high considering only the hospitalized patients (41.28%), and, older age, shortness of breath, the presence of comorbidities, and the ventilation requirement were more associated with the mortality of those patients. Looking at the results obtained in another country, the work of Imam et al [12] reported that only 15.3% of the hospitalized patients in Michigan, United States, did not survive from COVID-19.…”
Section: Plos Onementioning
confidence: 83%
“…A more general study conducted by Souza et al . [ 24 ] accounting for 208,969 hospitalized patients in Brazil, shows that the mortality rate in this country is high considering only the hospitalized patients (41.28%), and, older age, shortness of breath, the presence of comorbidities, and the ventilation requirement were more associated with the mortality of those patients. Looking at the results obtained in another country, the work of Imam et al .…”
Section: Discussionmentioning
confidence: 99%
“…In the first wave, likewise different countries, COVID-19 mainly affected elderly Brazilians with comorbidities [ 4 ]. On the other hand, empirical evidence has indicated a significant increase in the number of infected young adults (20-59 years old), admitted to the Intensive Care Unit (ICU), need for Invasive Mechanical Ventilation (IMV) as well as an increased mortality in this age group during the second wave.…”
mentioning
confidence: 99%