On saliva structures

Glantz, Per‐Olof; Baier, Robert E.; Friberg, Stig E.; Attström, Rolf

doi:10.1080/08927019109378208

Cited by 3 publications

(2 citation statements)

References 11 publications

(8 reference statements)

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“…2 This generally pessimistic view is challenged by a plethora of prior studies of salivary mucins, very similar to cervical glycoproteins, that do illustrate structural and functional changes (some of which co-vary with menstrual cycle days) with modified compositions. 3,4,5,6,7,8,9,10,11,12,13 In addition to observing P/S relationships over several menstrual cycles, the investigation repeated examination of ratios within 24-hour time-spans to determine whether the variance in sampling times altered the sample results and to identify the amount of change that normally occurs in the P/S ratio on a daily basis.…”

Section: Introductionmentioning

confidence: 99%

Daily Saliva and Vaginal Mucins Co-vary in Protein-to-Carbohydrate Ratio

Baier

Meyer

2018

JFB

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The currently reported study employed the curiously named (but simple) quantitative, nondestructive technique of Multiple Attenuated Internal Reflection InfraRed (MAIR-IR) spectroscopy to assess daily variations of both saliva and vaginal secretions from a panel of consenting volunteers. The project goal was to determine whether the protein-to-carbohydrate (starch) ratio, determined by MAIR-IR analysis of salivary and vaginal secretions is an objective measure of the co-variation of mucinous secretions with daily menstrual cycle. Overall, the spectral data were found to provide valid signatures of vaginal mucus chemical changes that also correlated with cyclic periods of presumed fertility, such periods exhibiting repeat times of 14-16 days and 27-29 days in the thoroughly analyzed records. At mid-cycle, associated with ovulatory events, the protein-to-carbohydrate ratio of vaginal mucin maximizes. Higher carbohydrate ratios are associated with stiffer cervical mucus plug formation, which usually prevents infection, spontaneous abortion, and pre-term birth, but may also be responsible for infertility. Mucin relaxation compounds, such as the FDA-approved oral rinse, delmopinol, may induce fertility in such cases.

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Section: Introductionmentioning

confidence: 99%

Daily Saliva and Vaginal Mucins Co-vary in Protein-to-Carbohydrate Ratio

Baier

Meyer

2018

JFB

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“…Whether co‐aggregation occurs in vivo , or only represents a model for co‐adhesion is an open question (3, 4). It has been argued that the concentration of co‐aggregating bacterial partners in saliva is too low for co‐aggregation to occur, while in addition, the fibrinous structure of saliva (5) restricts bacterial mobility. Brownian motion dynamics demonstrated that co‐adhesion contributes to the formation of ordered structures in dental plaque and is consequently more likely to occur in vivo (1).…”

mentioning

confidence: 99%

Co‐adhesion and removal of adhering bacteria from salivary pellicles by three different modes of brushing

Yang

Bos

Belder

et al. 2001

European J Oral Sciences

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This study compares removal of pairs of co-adhering and non-co-adhering oral actinomyces and streptococci by hand, electric and sonic brushing from salivary pellicles. In addition, re-deposition of a co-adhering and non-co-adhering streptococcal strain to brushed pellicles was studied. First, actinomyces were allowed to adhere to a pellicle in a flow chamber, after which streptococci suspended in saliva were perfused through the chamber at 33 C. Pellicles with adhering bacterial pairs were brushed and the number of bacteria remaining determined. Whereas sonic brushing removed nearly all adhering bacteria, greater numbers of larger aggregates of the co-adhering pair, involving Streptococcus oralis J22, were left behind after hand and electric brushing than of the non-co-adhering pair with Streptococcus sanguis PK1889. Re-deposition of streptococci to electrically and sonically brushed pellicles, however, was two-fold higher for the co-adhering pair than for the non-co-adhering pair. This demonstrates a role for co-adhesion in de novo plaque formation. Removal by the three different modes of brushing was not affected by the presence of fluoride, indicating that fluoride is not able to disrupt calcium bridges between co-adhering pairs. In contrast, in the presence of lactose only small aggregates of co-adhering pair were left behind.

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