“…For the noninvasive assessment of skin roughness, indirect replica-based techniques and direct in vivo techniques are in use [24,25]. Although fast and convenient direct methods that are appropriate for the clinical setting have been developed based on interference fringe profilometry and the use of CCD cameras [26,27,28], the preparation of replicas remains the most frequently used technique with a vast body of data available [3,4,5,8,10,12,13,17,18,29,30,31].…”