Olfactory dysfunction in man: Anatomical and behavioral aspects

Correlation between cerebral blood flow and olfactory function in mild cognitive impairment and Alzheimer's disease

“…Our findings were consistent with previously reported findings 22 of preserved odor detection 2,9 and impaired odor identification in patients with early AD. 6,8 Although there have been no previous reports of the use of SPECT to investigate the association between Abbreviaiton: ADAS, Alzheimer's Disease Assessment Scale.…”

“…Our findings were consistent with previously reported findings 22 of preserved odor detection 2,9 and impaired odor identification in patients with early AD 6 ,. 8 Although there have been no previous reports of the use of SPECT to investigate the association between CBF and olfactory function in patients with MCI or AD, there is consensus about the role of the temporal pole and entorhinal area in olfactory dysfunction, based on studies of the correlation between brain volume on MR images and olfactory dysfunction 4,10 .…”

Correlation between cerebral blood flow and olfactory function in mild cognitive impairment and Alzheimer's disease

“…Our findings were consistent with previously reported findings 22 of preserved odor detection 2,9 and impaired odor identification in patients with early AD. 6,8 Although there have been no previous reports of the use of SPECT to investigate the association between Abbreviaiton: ADAS, Alzheimer's Disease Assessment Scale.…”

“…Our findings were consistent with previously reported findings 22 of preserved odor detection 2,9 and impaired odor identification in patients with early AD 6 ,. 8 Although there have been no previous reports of the use of SPECT to investigate the association between CBF and olfactory function in patients with MCI or AD, there is consensus about the role of the temporal pole and entorhinal area in olfactory dysfunction, based on studies of the correlation between brain volume on MR images and olfactory dysfunction 4,10 .…”

Olfactory-evoked regional cerebral blood flow in Alzheimer's disease.

“…We hypothesized that olfactory sensory stimulation of patients with AD during PET would show reduced increases in mesial temporal rCBF in comparison to healthy elderly individuals. The results are at least partially consistent with this hypothesis: Control participants showed significant bilateral activation of the frontotemporal junction, the human analogue of piriform (primary olfactory) cortex (Eslinger, Damasio, & Van Hoesen, 1982;Gloor, 1997). R-AVT activation was also evident.…”

“Mind, body, and water!” – Postherpetic polydipsia masquerading as obsessive-compulsive disorder

“…[ 8 ] Whereas uncus is covered by part of olfactory cortex; hence, it is very intricately involved in olfaction. [ 9 ] We hypothesize that, in our case, the involvement of ACC probably caused the obsessive symptoms. Furthermore, dysfunctional uncus sequentially caused the persistent halitosis, which, afterward, was channelized to florid polydipsic behavior with further involvements of hippocampus and limbic system,[ 10 ] key components for thirst regulation [ Figure 1 ].…”

Correlation between cerebral blood flow and olfactory function in mild cognitive impairment and Alzheimer's disease

“…Our findings were consistent with previously reported findings 22 of preserved odor detection 2,9 and impaired odor identification in patients with early AD. 6,8 Although there have been no previous reports of the use of SPECT to investigate the association between Abbreviaiton: ADAS, Alzheimer's Disease Assessment Scale.…”

“…Our findings were consistent with previously reported findings 22 of preserved odor detection 2,9 and impaired odor identification in patients with early AD 6 ,. 8 Although there have been no previous reports of the use of SPECT to investigate the association between CBF and olfactory function in patients with MCI or AD, there is consensus about the role of the temporal pole and entorhinal area in olfactory dysfunction, based on studies of the correlation between brain volume on MR images and olfactory dysfunction 4,10 .…”

Olfactory-evoked regional cerebral blood flow in Alzheimer's disease.

“…We hypothesized that olfactory sensory stimulation of patients with AD during PET would show reduced increases in mesial temporal rCBF in comparison to healthy elderly individuals. The results are at least partially consistent with this hypothesis: Control participants showed significant bilateral activation of the frontotemporal junction, the human analogue of piriform (primary olfactory) cortex (Eslinger, Damasio, & Van Hoesen, 1982;Gloor, 1997). R-AVT activation was also evident.…”

“Mind, body, and water!” – Postherpetic polydipsia masquerading as obsessive-compulsive disorder

“…[ 8 ] Whereas uncus is covered by part of olfactory cortex; hence, it is very intricately involved in olfaction. [ 9 ] We hypothesize that, in our case, the involvement of ACC probably caused the obsessive symptoms. Furthermore, dysfunctional uncus sequentially caused the persistent halitosis, which, afterward, was channelized to florid polydipsic behavior with further involvements of hippocampus and limbic system,[ 10 ] key components for thirst regulation [ Figure 1 ].…”

Correlation between cerebral blood flow and olfactory function in mild cognitive impairment and Alzheimer's disease

“…Our findings were consistent with previously reported findings 22 of preserved odor detection 2,9 and impaired odor identification in patients with early AD. 6,8 Although there have been no previous reports of the use of SPECT to investigate the association between Abbreviaiton: ADAS, Alzheimer's Disease Assessment Scale.…”

“…Our findings were consistent with previously reported findings 22 of preserved odor detection 2,9 and impaired odor identification in patients with early AD 6 ,. 8 Although there have been no previous reports of the use of SPECT to investigate the association between CBF and olfactory function in patients with MCI or AD, there is consensus about the role of the temporal pole and entorhinal area in olfactory dysfunction, based on studies of the correlation between brain volume on MR images and olfactory dysfunction 4,10 .…”

Olfactory-evoked regional cerebral blood flow in Alzheimer's disease.

“…We hypothesized that olfactory sensory stimulation of patients with AD during PET would show reduced increases in mesial temporal rCBF in comparison to healthy elderly individuals. The results are at least partially consistent with this hypothesis: Control participants showed significant bilateral activation of the frontotemporal junction, the human analogue of piriform (primary olfactory) cortex (Eslinger, Damasio, & Van Hoesen, 1982;Gloor, 1997). R-AVT activation was also evident.…”

“Mind, body, and water!” – Postherpetic polydipsia masquerading as obsessive-compulsive disorder

“…[ 8 ] Whereas uncus is covered by part of olfactory cortex; hence, it is very intricately involved in olfaction. [ 9 ] We hypothesize that, in our case, the involvement of ACC probably caused the obsessive symptoms. Furthermore, dysfunctional uncus sequentially caused the persistent halitosis, which, afterward, was channelized to florid polydipsic behavior with further involvements of hippocampus and limbic system,[ 10 ] key components for thirst regulation [ Figure 1 ].…”