Office nail fold capillary microscopy using ophthalmoscope

Minkin, Wilfred; Rabhan, Nathan B.

doi:10.1016/s0190-9622(82)70107-0

Cited by 34 publications

(12 citation statements)

References 7 publications

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“…A skin biopsy, performed in 12-6% of all our referrals, usually served to narrow the differential diagnosis or to confirm an informed clinical suspicion, rather than to provide a diagnosis which was totally unsuspected clinically. Other simple investigations, including skin scraping for microscopy and fungal culture, Tzanck smears and ophthalmoscopic investigation of nail fold capillaries (Minkin & Rabhan, 1982), were also valuable and easily performed and deserve to be taught to nondermatologists.…”

Section: Discussionmentioning

confidence: 99%

Patterns of dermatology referrals in a general hospital

Hardwick

Saxe

1986

Br J Dermatol

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A survey of 500 patients hospitalized in non-dermatology wards and referred for dermatological opinion is reported. In approximately 50%, the skin lesions were related to the presenting illness; in 36.6% of these patients the skin condition contributed substantially to the diagnosis of the systemic disease. This study emphasizes the considerable interface between cutaneous and systemic disease and the need for close co-operation between medical and dermatology departments. The implications for postgraduate education are highlighted, since such patients are infrequently seen in a dermatology out-patient setting.

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Section: Discussionmentioning

confidence: 99%

Patterns of dermatology referrals in a general hospital

Hardwick

Saxe

1986

Br J Dermatol

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“…[1][2][3][4][5][6] Furthermore, NVC changes are as prevalent and as prominent in dermatomyositis (DM) as in SSD. 7,8 However, such findings are not frequently detected in patients with other connective tissue diseases. The routine use of capillaroscopy at the bedside has yet to become fully integrated into standard clinical practice, because the equipment is relatively expensive and not easily portable.…”

Section: Introductionmentioning

confidence: 99%

“…Distinct NVC patterns may also be useful in evaluating the severity and stage of SSD microvascular damage 1–6 . Furthermore, NVC changes are as prevalent and as prominent in dermatomyositis (DM) as in SSD 7,8 . However, such findings are not frequently detected in patients with other connective tissue diseases.…”

Section: Introductionmentioning

confidence: 99%

Dermoscopy findings of nail fold capillaries in connective tissue diseases

Hasegawa

2010

The Journal of Dermatology

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Nail fold (video) capillaroscopy is a well-established technique to assess patients with Raynaud's phenomenon, in whom specific abnormalities of capillaries are predictive of underlying systemic sclerosis and its related diseases (scleroderma spectrum disorder). The typical abnormalities are also found in patients with dermatomyositis and those findings are useful for the assessment of vascular injury and the evaluation of therapeutic effect in patients with scleroderma spectrum disorder and dermatomyositis. Recently, it has been suggested that dermoscopy can replace the capillaroscopy in significant part for detection of nail fold capillary abnormalities. In this review, I summarized the established capillaroscopy findings in connective tissues diseases and tried to apply the findings of dermoscopy to the findings and classification of capillaroscopy.

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“…The patterns of SD and SLE revealed by this technique have been clearly defined (9-14). On the other hand, few investigations have dealt ?with the results of NCM in MCTD (15,16). To determine the chief characteristics of skin microangiopathy in mixed connective tissue disease, we therefore compared the results of NCM in this disease with those of systemic sclerosis and systemic lupus erythematosus.…”

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confidence: 99%

Nailfold capillary microscopy in mixed connective tissue disease. Comparison with systemic sclerosis and systemic lupus erythematosus

Granier

Vayssairat

Priollet

et al. 1986

Arthritis & Rheumatism

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Nailfold capillary microscopy patterns in 22 patients with mixed connective tissue disease (MCTD) were compared with those of 21 patients with systemic lupus erythematosus (SLE) and 30 patients with systemic sclerosis (scleroderma [SD]). Microvascular data were classified blindly as follows: normal, nonspecific abnormalities, SD pattern, and SLE pattern, with special attention to the presence of dystrophic, branched "bushy" capillary formations. Of the 22 patients with MCTD, 63.6% had an SD pattern, 22.7% had an SLE pattern, 13.6% had nonspecific abnormalities, and 72.7% had bushy capillary formations. Compared with SLE microangiopathy, MCTD microangiopathy exhibited significantly greater capillary loss (P < 0.05), more frequent SD patterns (P < 0.001), and more frequent bushy capillaries (P < 0.001). Compared with SD patients, MCTD patients displayed less frequent SD patterns (P < 0.02) and more frequent bushy capillary formations (P < 0.01). The presence of bushy capillaries was suggestive of MCTD. For diagnostic purposes, bushy capillaries displayed 72% sensitivity, 80% specificity, and 87.2% negative predictive value. The quantitative and qualitative expressions of microangiopathy were different in MCTD and SLE, respectively. This supports the hypothesis that each disease is a distinct entity. Nevertheless, there were many resemblances

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Office nail fold capillary microscopy using ophthalmoscope

Cited by 34 publications

References 7 publications

Patterns of dermatology referrals in a general hospital

Patterns of dermatology referrals in a general hospital

Dermoscopy findings of nail fold capillaries in connective tissue diseases

Nailfold capillary microscopy in mixed connective tissue disease. Comparison with systemic sclerosis and systemic lupus erythematosus

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