Design. In this cross-sectional study, we investigated 833 Caucasian men, aged 71 ± 0.6 years, to determine the association between plasma 25(OH)D concentrations, measured with high-pressure liquid chromatography mass spectrometry, and the prevalence of hypertension. We used both supine office and 24-h BP measurements for classifying participants as normotensive or confirmed hypertensive; participants with inconsistent classifications were excluded.Results. In a multivariable adjusted logistic regression model, men with 25(OH)D concentrations <37.5 nmol L )1 had a 3-fold higher prevalence of confirmed hypertension compared to those with ‡37.5 nmol L )1 25(OH)D (odds ratio = 3.3, 95% CI: 1.0-11.0).
Conclusions.Our results show that low plasma 25(OH)D concentration is associated with a higher prevalence of confirmed hypertension.