Ocular Surface Findings in Patients With Lichen Planopilaris

Abstract

Patients with LPP, scored worse in ocular surface tests. This finding warrants special scrutiny for dry eye and MG dysfunction in these patients.

Evaluation of corneal densitometry changes in patients with lichen planus

“…Sanlı et al also found a decrease in the Schirmer's I test but they also reported significant differences in the conjunctival lissamine green staining scores and conjunctival impression‐cytology degrees 5 . By contrast, some researchers reported the presence of meibomian gland dysfunction in patients with lichen planus but found no effect on the Schirmer's I test results 20 …”

“…5 By contrast, some researchers reported the presence of meibomian gland dysfunction in patients with lichen planus but found no effect on the Schirmer's I test results. 20 The presence of dry eye and punctate epitheliopathy is known to affect corneal densitometry measurements. Researchers found that corneal backward light scattering was more common in patients with severe dry eyes.…”

Evaluation of ocular psoriasis with meibography

“…Therefore, having a scalp disease such as psoriasis, lichen planopilaris may occur a risk for MGD and DED. 27 On the other hand, several studies indicate an association of MGD with inflammatory ocular surface diseases such as Sjögren, conjunctival epithelium could be a direct target of the inflammatory process that leads to the lymphocyte infiltration in the tarsal conjunctiva, and additionally, direct involvement of sebaceous glands occurs in patients with lichen planopilaris 28 , 29 , 30 and, similarly, this involvement may be explained with this mechanism in psoriasis which is a chronic immune-mediated inflammatory disease by T-lymphocytes and dendritic cells.…”

Ocular involvement and complications of lichen planus, lichen planus pigmentosus, and lichen planopilaris: A comprehensive review

“…18 Blepharitis and MGD, present in one-third of patients with LP, further worsen the dry eye vicious cycle by impairing the lipid layer production of the tear film. 44,48 MG involvement in lichenoid dermatoses results from direct lymphocyte infiltration of the epithelium of the tarsal conjunctiva. 44 Absence of sebaceous glands is observed in patients with LPL.…”

“…44,48 MG involvement in lichenoid dermatoses results from direct lymphocyte infiltration of the epithelium of the tarsal conjunctiva. 44 Absence of sebaceous glands is observed in patients with LPL. Such finding might explain the MGD observed in LPL.…”