Ocular Pemphigus

Preliminary Examination of Rabbit Conjunctival Mucins

“…Keyphrasee 0 Mucins-isolation from rabbit conjunctiva, fractionation by gel filtration and anion-exchange chromatography, determination of molecular weight, role in tear film stability Conjunctival mucinsisolation from rabbits, fractionation by gel filtration and anion-exchange chromatography, determination of molecular weight, role in tear film stability 0 Ocular mucins-isolation from rabbit conjunctiva, fractionation by gel filtration and anion-exchange chromatography, determination of molecular weight, role in tear film stability The strategic role assumed by Conjunctival mucin in tear film stability has been recognized, but not understood, for many years. Alteration in either its chemical nature or quantity (probably both) has been implicated in keratoconjunctivitis sicca as well as other dry-eye syndromes (1)(2)(3)(4)(5), all of which are characterized by poor wetting of the corneal epithelium. It has been proposed that this fascinating substance derives its role from both the surface activity it is expected to exhibit at the air-tear and tearcorneal epithelium interfaces and the molecular events following its absorption at these two interfaces.…”

Preliminary Examination of Rabbit Conjunctival Mucins

“…Keyphrasee 0 Mucins-isolation from rabbit conjunctiva, fractionation by gel filtration and anion-exchange chromatography, determination of molecular weight, role in tear film stability Conjunctival mucinsisolation from rabbits, fractionation by gel filtration and anion-exchange chromatography, determination of molecular weight, role in tear film stability 0 Ocular mucins-isolation from rabbit conjunctiva, fractionation by gel filtration and anion-exchange chromatography, determination of molecular weight, role in tear film stability The strategic role assumed by Conjunctival mucin in tear film stability has been recognized, but not understood, for many years. Alteration in either its chemical nature or quantity (probably both) has been implicated in keratoconjunctivitis sicca as well as other dry-eye syndromes (1)(2)(3)(4)(5), all of which are characterized by poor wetting of the corneal epithelium. It has been proposed that this fascinating substance derives its role from both the surface activity it is expected to exhibit at the air-tear and tearcorneal epithelium interfaces and the molecular events following its absorption at these two interfaces.…”

THE ULTRASTRUCTURE OF THE NORMAL CONJUNCTIVAL EPITHELIUM OF THE GUINEA PIG: III. The Bulbar Zone, the Zone of the Fornix and the Supranodular Zone

“…Previous electron microscopic investigations of the bulbar and fornical zones of the conjunctiva are few: a short description of the normal epithelium included in a study on ocular pemphigus (Carroll & Kuwabara 1968), a report on surface properties of the bulbar epithelium (Radn6t 1971), and a short survey of bulbar, fornical and tarsal conjunctiva (Weingeist 1973). The supranodular zone has not previously been studied.…”

The Ultrastructure of the Normal Conjunctival Epithelium of the Guinea Pig

“…A short report on bulbar conjunctiva was included in a study of ocular pemphigus (Carroll & Kuwabara 1968), and a very short survey of bulbar, fornical and tarsal conjunctiva was published by Weingeist (1973). In older studies, in which specimens may have also been taken from the fornices, the descriptions are generally less comprehensive and to a large extent concentrated upon certain cell organelles, cell types or intercellular relations (Suzuki 1956(Suzuki , 1957 de Toledo et al 1957;Shibuya 1958;Fujiyama 1961;Segawa 1962; de Toledo 1966).…”

Preliminary Examination of Rabbit Conjunctival Mucins

“…Keyphrasee 0 Mucins-isolation from rabbit conjunctiva, fractionation by gel filtration and anion-exchange chromatography, determination of molecular weight, role in tear film stability Conjunctival mucinsisolation from rabbits, fractionation by gel filtration and anion-exchange chromatography, determination of molecular weight, role in tear film stability 0 Ocular mucins-isolation from rabbit conjunctiva, fractionation by gel filtration and anion-exchange chromatography, determination of molecular weight, role in tear film stability The strategic role assumed by Conjunctival mucin in tear film stability has been recognized, but not understood, for many years. Alteration in either its chemical nature or quantity (probably both) has been implicated in keratoconjunctivitis sicca as well as other dry-eye syndromes (1)(2)(3)(4)(5), all of which are characterized by poor wetting of the corneal epithelium. It has been proposed that this fascinating substance derives its role from both the surface activity it is expected to exhibit at the air-tear and tearcorneal epithelium interfaces and the molecular events following its absorption at these two interfaces.…”

THE ULTRASTRUCTURE OF THE NORMAL CONJUNCTIVAL EPITHELIUM OF THE GUINEA PIG: III. The Bulbar Zone, the Zone of the Fornix and the Supranodular Zone

“…Previous electron microscopic investigations of the bulbar and fornical zones of the conjunctiva are few: a short description of the normal epithelium included in a study on ocular pemphigus (Carroll & Kuwabara 1968), a report on surface properties of the bulbar epithelium (Radn6t 1971), and a short survey of bulbar, fornical and tarsal conjunctiva (Weingeist 1973). The supranodular zone has not previously been studied.…”

The Ultrastructure of the Normal Conjunctival Epithelium of the Guinea Pig

“…A short report on bulbar conjunctiva was included in a study of ocular pemphigus (Carroll & Kuwabara 1968), and a very short survey of bulbar, fornical and tarsal conjunctiva was published by Weingeist (1973). In older studies, in which specimens may have also been taken from the fornices, the descriptions are generally less comprehensive and to a large extent concentrated upon certain cell organelles, cell types or intercellular relations (Suzuki 1956(Suzuki , 1957 de Toledo et al 1957;Shibuya 1958;Fujiyama 1961;Segawa 1962; de Toledo 1966).…”

Preliminary Examination of Rabbit Conjunctival Mucins

“…Keyphrasee 0 Mucins-isolation from rabbit conjunctiva, fractionation by gel filtration and anion-exchange chromatography, determination of molecular weight, role in tear film stability Conjunctival mucinsisolation from rabbits, fractionation by gel filtration and anion-exchange chromatography, determination of molecular weight, role in tear film stability 0 Ocular mucins-isolation from rabbit conjunctiva, fractionation by gel filtration and anion-exchange chromatography, determination of molecular weight, role in tear film stability The strategic role assumed by Conjunctival mucin in tear film stability has been recognized, but not understood, for many years. Alteration in either its chemical nature or quantity (probably both) has been implicated in keratoconjunctivitis sicca as well as other dry-eye syndromes (1)(2)(3)(4)(5), all of which are characterized by poor wetting of the corneal epithelium. It has been proposed that this fascinating substance derives its role from both the surface activity it is expected to exhibit at the air-tear and tearcorneal epithelium interfaces and the molecular events following its absorption at these two interfaces.…”

THE ULTRASTRUCTURE OF THE NORMAL CONJUNCTIVAL EPITHELIUM OF THE GUINEA PIG: III. The Bulbar Zone, the Zone of the Fornix and the Supranodular Zone

“…Previous electron microscopic investigations of the bulbar and fornical zones of the conjunctiva are few: a short description of the normal epithelium included in a study on ocular pemphigus (Carroll & Kuwabara 1968), a report on surface properties of the bulbar epithelium (Radn6t 1971), and a short survey of bulbar, fornical and tarsal conjunctiva (Weingeist 1973). The supranodular zone has not previously been studied.…”

The Ultrastructure of the Normal Conjunctival Epithelium of the Guinea Pig

“…A short report on bulbar conjunctiva was included in a study of ocular pemphigus (Carroll & Kuwabara 1968), and a very short survey of bulbar, fornical and tarsal conjunctiva was published by Weingeist (1973). In older studies, in which specimens may have also been taken from the fornices, the descriptions are generally less comprehensive and to a large extent concentrated upon certain cell organelles, cell types or intercellular relations (Suzuki 1956(Suzuki , 1957 de Toledo et al 1957;Shibuya 1958;Fujiyama 1961;Segawa 1962; de Toledo 1966).…”