Ocular Manifestations of Hypercupremia Associated With Multiple Myeloma

The Nature of Capsular Inclusions in Lenticular Chalcosis

“…In later years reports of the "ocular copper syndrome" in multiple myeloma have been published (Ellis 1969; Lewis et al 1975). The findings here do not differ from Wilson's disease or chalcosis due to intraocular foreign bodies.…”

The Nature of Capsular Inclusions in Lenticular Chalcosis

“…In later years reports of the "ocular copper syndrome" in multiple myeloma have been published (Ellis 1969; Lewis et al 1975). The findings here do not differ from Wilson's disease or chalcosis due to intraocular foreign bodies.…”

Ophthalmic Manifestations of Multiple Myeloma

“…Other ocular findings including crystal [6, 7, 10, 11]or copper deposits [5, 9]in the cornea and ciliary body cysts [4, 8, 12, 13, 30]were not observed in this series. These are frequently asymptomatic.…”

Corneal opacity and copper levels of the Lewis syndrome after systemic chemotherapy

“…5 In the case of Lewis syndrome the IgG has a marked affinity for copper. 6 , 9 The chemotherapy of our proband led to a complete remission of the MM and at the same time to normal copper values in the serum over five years. This is further evidence of the unique IgG nature in the context of Lewis syndrome.…”

“…The authors reported a 30-year long term follow-up of this patient 10 who was first examined in 1975. 6 She was in excellent health. The only apparent systemic manifestation of hypercupremia was her copper-colored hair.…”

The Nature of Capsular Inclusions in Lenticular Chalcosis

“…In later years reports of the "ocular copper syndrome" in multiple myeloma have been published (Ellis 1969; Lewis et al 1975). The findings here do not differ from Wilson's disease or chalcosis due to intraocular foreign bodies.…”

Ophthalmic Manifestations of Multiple Myeloma

“…Other ocular findings including crystal [6, 7, 10, 11]or copper deposits [5, 9]in the cornea and ciliary body cysts [4, 8, 12, 13, 30]were not observed in this series. These are frequently asymptomatic.…”

Corneal opacity and copper levels of the Lewis syndrome after systemic chemotherapy

“…5 In the case of Lewis syndrome the IgG has a marked affinity for copper. 6 , 9 The chemotherapy of our proband led to a complete remission of the MM and at the same time to normal copper values in the serum over five years. This is further evidence of the unique IgG nature in the context of Lewis syndrome.…”

“…The authors reported a 30-year long term follow-up of this patient 10 who was first examined in 1975. 6 She was in excellent health. The only apparent systemic manifestation of hypercupremia was her copper-colored hair.…”

The Nature of Capsular Inclusions in Lenticular Chalcosis

“…In later years reports of the "ocular copper syndrome" in multiple myeloma have been published (Ellis 1969; Lewis et al 1975). The findings here do not differ from Wilson's disease or chalcosis due to intraocular foreign bodies.…”

Ophthalmic Manifestations of Multiple Myeloma

“…Other ocular findings including crystal [6, 7, 10, 11]or copper deposits [5, 9]in the cornea and ciliary body cysts [4, 8, 12, 13, 30]were not observed in this series. These are frequently asymptomatic.…”

Corneal opacity and copper levels of the Lewis syndrome after systemic chemotherapy

“…5 In the case of Lewis syndrome the IgG has a marked affinity for copper. 6 , 9 The chemotherapy of our proband led to a complete remission of the MM and at the same time to normal copper values in the serum over five years. This is further evidence of the unique IgG nature in the context of Lewis syndrome.…”

“…The authors reported a 30-year long term follow-up of this patient 10 who was first examined in 1975. 6 She was in excellent health. The only apparent systemic manifestation of hypercupremia was her copper-colored hair.…”