Ocimum sanctum essential oil and its active principles exert their antifungal activity by disrupting ergosterol biosynthesis and membrane integrity

Anesthetic activity of plant essential oils on <i>Cyprinus carpio</i> (koi carp)

“…Eugenol was also existed (11.56%) but significantly lower amount than methyl eugenol. These results are similar to the findings of the other previous reports (46)(47)(48). Methyl eugenol has been reviewed to have anesthetic activity (49).…”

Chemical composition of the essential oil of Ocimum tenuiflorum L. (Krishna Tulsi) from North West Karnataka, India

“…It is interesting to note that chemotypes containing other compounds have also been reported (Khan et al, 2010;Kicel et al, 2005;Machado et al, 1999;Brophy et al, 1993;Pino et al, 1998). This report presents low amount of methyl eugenol as compared to the earlier report (Joshi, 2013a) from the essential oil of O. tenuiflorum collected from North West Karnataka, India.…”

“…Anticancer (Kathiresan, Guanasekan, Rammurthy, & Govidswami, 1999), radioprotective, anticarcinogenic (Devi, 2001), antioxidant (Devi, 2001;Joshi, 2013a), chemopreventive (Prashar, Kumar, Banerjee, & Rao, 1994;Karthikeyan, Ravichadran, & Govindasamy, 1999), immunotherapeutic (Mukherjee, Das, & Ram, 2005), antimicrobial (Singh, Malhotra, & Majumdar, 2005;Joshi, 2013a), anti-inflammatory (Godhwani, Godhwani, & Vyas, 1987;Singh & Majumdar, 1997), analgesic, antipyretic (Godhwani et al, 1987), antispermatogenic (Seth, Johri, & Sundaram, 1981) and antistress (Bhargava & Singh, 1981) activities of this plant have also been reported. The essential oils of O. tenuiflorum have been reported to possess methyl eugenol (Joshi, 2013a), methyl eugenol, β-caryophyllene (Bhattacharya, Kaul, & Rajeswara Rao, 1996;Kothari, Bhattacharya, Ramesh, Garg, & Khanuja, 2005), methyl eugenol, (E)-caryophyllene, eugenol and, β-elemene (Awasthi & Dixit, 2007), methyl chavicol, and linalool (Khan et al, 2010) from India; β-bisabolene, 1,8-cineole and methyl chavicol (Kicel, Kurowska, & Kalemba, 2005) from Poland; methyl eugenol and isocaryophyllene (Gbolade & Lockwood, 2008) from Nigeria; eugenol, β-caryophyllene and caryophyllene oxide (Machado, Silva, Matos, Craveiro, & Alencar, 1999) from Northeastern Brazil; eugenol, β-elemene and β-caryophyllene (Pino, Rosado, Rodriguez, & Garcia, 1998) from Cuba; methyl chavicol, camphor and β-caryophyllene (Brophy, Goldsack, & Clarkson, 1993) from Australia. The aim of the present study was to investigate the essential oil composition of O. tenuiflorum (Krishna Tulsi) growing in North West Karnataka, India, using gas chromatography (GC) and gas chromatography-mass spectrometry (GC-MS) analyses.…”

Atividade anti-Candida tropicalis dos enantiômeros (R)-(+)- & (S)-(-)-citronelal em associação com nistatina

“…Além disso, há poucos antifúngicos disponíveis para tratar infecções causadas por esses fúngos. A classe dos antifúngicos azólicos é amplamente utilizada, infelizmente são geralmente fungistáticos, em vez de fungicida, e seu uso prolongado contribui para o desenvolvimento de cepas resistentes 26,27 . A nistatina, mesmo em sua formulação convencional, produz efeitos tóxicos que limitam seu uso parenteral, restringindo-se a aplicações superficiais 28 .…”