Occurrence, public health hazards and detection methods of antibiotic residues in foods of animal origin: A comprehensive review

Vishnuraj, M. R.; Kandeepan, G.; Rao, K. H.; Chand, Sagar; Kumbhar, V.

doi:10.1080/23311932.2016.1235458

Cited by 46 publications

(38 citation statements)

References 17 publications

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“…These withdrawal periods have been established to prevent the occurrence of antibiotic residues in animal products above the MRLs as laid down in Regulation (EU) 37/2010. Antibiotics use may result in the presence of antibiotic residues in the milk when milk is delivered within the withdrawal period (Vishnuraj and others ). For food safety, but also for technical reasons, the dairy industry established private monitoring programs focusing on antibiotic residues.…”

Section: Resultsmentioning

confidence: 99%

Overview of Food Safety Hazards in the European Dairy Supply Chain

Asselt

Fels‐Klerx

Marvin

et al. 2016

Comp Rev Food Sci Food Safe

136

127

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Monitoring of dairy products should preferably focus on the most relevant food safety hazards in the dairy supply chain. For this purpose, the possible presence of microbiological, chemical, and physical hazards as well as trends in the dairy supply chain that may affect their presence were assessed. A literature review was combined with available data from EFSA, RASFF, and the Dutch monitoring program on chemical hazards as well as expert information. This study revealed that microbiological hazards are encountered more frequently in dairy products than chemical and physical hazards. Listeria monocytogenes, Staphylococcus aureus, Salmonella, and human pathogenic Escherichia coli were identified as the most important microbiological hazards in dairy products. Soft and semisoft cheeses are most frequently associated with L. monocytogenes and S. aureus enterotoxins, whereas raw milk is most frequently associated with human pathogenic E. coli and Campylobacter spp., Cronobacter spp., and Salmonella spp. are the microbiological hazards of most concern in powdered infant formula. Based on literature, monitoring, and RASFF data, the most relevant chemical hazards in dairy products are aflatoxin M 1 , dioxins, and dioxin-like compounds and residues of veterinary drugs. Chemical hazards primarily occur at the dairy farm and may accumulate during further processing. The most relevant physical hazards are metal, glass, and plastic particles introduced during processing. Analysis of trends in the near future revealed that increased milk production is seen as most relevant in relation to food safety. Other trends affecting food safety are climate change and changes at the farm level, which aim to improve animal welfare and environmental sustainability.

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Section: Resultsmentioning

confidence: 99%

Overview of Food Safety Hazards in the European Dairy Supply Chain

Asselt

Fels‐Klerx

Marvin

et al. 2016

Comp Rev Food Sci Food Safe

136

127

View full text Add to dashboard Cite

show abstract

“…According to Vishnuraj et al [6], other measures that could be adopted to reduce antimicrobial residues in meat and meat products include (1) reduction of antimicrobial usage in livestock production (as many developed countries have banned its usage as growth promoters), (2) enforcement of appropriate withdrawal periods of antimicrobial drugs application by government authorities or regulatory bodies before livestock slaughter (3) creation of mass awareness on implication of antimicrobial drugs residues in meat and meat products among consumers, and individual farmer, (4) livestock producer should be educated on farm management, hygiene practices and antimicrobial usages in order to prevent occurrence of antimicrobial residues in meat production and lastly (5) rapid screening methods should be developed for detecting and segregating samples contains above antimicrobial residues before the food products get to consumers. More so, establishment of framework to proper monitoring of drug usage and surveillance of antimicrobial resistance would be of great advantage [105].…”

Section: Other Measures For Solutionmentioning

confidence: 99%

“…At present the global average annual consumption of antimicrobials per kilogram of animal produced is estimated at >100 mg/kg [6]. It has also been showed that about 80% of all the antibiotics administered in veterinary field are used as growth promoters and in most cases, this exceeds the total antibiotics use for human medical care [6]. In a study, Aarestrup [7] observed that global consumption of antibiotic in animals is twice that of humans.…”

Section: Introductionmentioning

confidence: 99%

Veterinary Drug Residues in Meat and Meat Products: Occurrence, Detection and Implications

Falowo¹,

Akimoladun²

2020

Veterinary Medicine and Pharmaceuticals

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Application of veterinary drugs in livestock production is inevitable as they are essential for treatment of diseases, prevention of diseases, modification of physiological functions, improvement of growth and productivity as well as for ensuring food safety. However, recent reports have revealed that the use of veterinary drugs in large amounts and consistently could result in deposition of antimicrobial residues in muscle and organs of animal. Consumption of these residues in animal products may pose health risk to consumers including development of antibiotic resistance bacteria, allergy, reproductive disorder and hypersensitivity reaction. It is in line with this that this chapter seeks to examine the cause, occurrence, mode of detection, health implication and possible solution to veterinary drugs residues in meat and meat products.

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“…Throughout the world, there is an emerging public health crisis and a growing concern regarding the potential for the development of antimicrobial resistance (AMR) that can occur as a result of the selective pressure and dissemination of resistance caused by unscrupulous misuse and inappropriate antimicrobial usage [1,9,13,19]. Over time, 10 the restriction of antibiotic usage has been encouraged, if not enacted through legislation, in an attempt to prevent such AMR development due to non-rational veterinary antimicrobial use [10].…”

Section: Introductionmentioning

confidence: 99%

“…Over time, 10 the restriction of antibiotic usage has been encouraged, if not enacted through legislation, in an attempt to prevent such AMR development due to non-rational veterinary antimicrobial use [10]. However, despite this, by 2030, the global use of antimicrobials in food animal production is expected to increase by 67 % compared to the 2010 usage levels [18,19].…”

Section: Introductionmentioning

confidence: 99%

Broad Spectrum Detection of Antibiotic Residues in Poultry Meat by a Multi-Plate Assay

Watkins

Kožárová

2019

Folia Veterinaria

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The objective of this study was to use the “Screening test for antibiotic residues” (STAR) as a broad-spectrum detection method for antibiotic residues in poultry meat. The STAR method is a microbiological inhibition assay (a five plate test) where the development of inhibition zones (IZs) indicates the presence of antibiotic residues in meat samples. By using the STAR method, in a total of 13 poultry products providing 18 meat samples (14 muscle and 4 skin) and 18 corresponding juice samples, 11 out of the 18 samples were positive for containing antibiotic residues. Based on muscle alone (which is the matrix validated for use in the STAR method), 6 of the 14 muscle samples were positive for antibiotic residues. The STAR method as a screening technique proves advantageous as it is relatively easy to perform and of a low cost. Furthermore, the STAR method not only indicates the presence or absence of antibacterial substances, but simultaneously, a positive sample gives an indication of the antibiotic family present due to the use of five different bacterial test organisms. Families of antibiotics pre-identified due to positive samples in the results of this study include aminoglycosides (one out of 18), beta-lactams and sulphonamides (6 out of 18), and macrolides (5 out of 18). Such pre-identification of the antimicrobial families allows for a targeted confirmatory analysis. However, one could argue that the STAR method is laborious and time consuming. Overall, given the potential for false positive/negative results, further confirmatory method analysis of the samples must be performed to ensure that the results and conclusions drawn here are true.

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Occurrence, public health hazards and detection methods of antibiotic residues in foods of animal origin: A comprehensive review

Cited by 46 publications

References 17 publications

Overview of Food Safety Hazards in the European Dairy Supply Chain

Overview of Food Safety Hazards in the European Dairy Supply Chain

Veterinary Drug Residues in Meat and Meat Products: Occurrence, Detection and Implications

Broad Spectrum Detection of Antibiotic Residues in Poultry Meat by a Multi-Plate Assay

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