2017
DOI: 10.1136/oemed-2016-103953
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Occupational factors and markers of ovarian reserve and response among women at a fertility centre

Abstract: Objectives To explore whether work schedules and physically demanding work were associated with markers of ovarian reserve and response. Methods This analysis included women (n=473 and n=313 for ovarian reserve and ovarian response analysis, respectively) enrolled in a prospective cohort study of couples presenting to an academic fertility center (2004–2015). Information on occupational factors was collected on a take-home questionnaire, and reproductive outcomes were abstracted from electronic medical recor… Show more

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Cited by 31 publications
(22 citation statements)
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“…Maternal vigorous activity prior to ART treatment was positively associated with probability of live birth among women of normal BMI but not among overweight or obese women (Gaskins, et al, 2016). Within occupational factors, women who reported lifting/moving heavy objects at work had fewer total and mature oocytes, as well as a small reduction in mean AFC, compared with women who reported never lifting/moving heavy objects (Minguez-Alarcon, et al, 2017).…”
Section: Resultsmentioning
confidence: 99%
“…Maternal vigorous activity prior to ART treatment was positively associated with probability of live birth among women of normal BMI but not among overweight or obese women (Gaskins, et al, 2016). Within occupational factors, women who reported lifting/moving heavy objects at work had fewer total and mature oocytes, as well as a small reduction in mean AFC, compared with women who reported never lifting/moving heavy objects (Minguez-Alarcon, et al, 2017).…”
Section: Resultsmentioning
confidence: 99%
“…In this circumstance, perturbation of the LH surge may disrupt the cyclicity of ovulation in women who otherwise do not have anovulatory infertility or poor ovarian reserve. In a prospective study of couples attending a fertility center, women who worked evening/night/rotating shifts had significantly lower oocyte yield following controlled ovarian stimulation compared to day workers, but no difference in measures of ovarian reserve, such as antral follicle count and follicle stimulating hormone (40).…”
Section: Discussionmentioning
confidence: 98%
“…In addition to decreased childbearing rates and fecundability, young shift workers are more likely to required fertility treatment to conceive [ 85 ]. The influence of shiftwork extends past requiring fertility treatments [ 85 ] and has been documented to influence the success of fertility treatments [ 86 ]. In a population of women attending an academic fertility treatment center, reduced mature oocyte yields have been documented in women working evening/night/rotating shifts compared to day shift workers [ 86 ].…”
Section: Chronic Shiftwork Negatively Impacts Fertility In Womenmentioning
confidence: 99%
“…The influence of shiftwork extends past requiring fertility treatments [ 85 ] and has been documented to influence the success of fertility treatments [ 86 ]. In a population of women attending an academic fertility treatment center, reduced mature oocyte yields have been documented in women working evening/night/rotating shifts compared to day shift workers [ 86 ]. One possible explanation for the decreased childbearing rate for rotating shift workers is that it could be linked with disruptions found in the menstrual cycles of shift workers [ 4 , 5 , 6 ] via hormone disruption [ 126 ].…”
Section: Chronic Shiftwork Negatively Impacts Fertility In Womenmentioning
confidence: 99%