Observations of ventilation during resuscitation in a canine model

Arterial blood gas changes during cardiac arrest and cardiopulmonary resuscitation combined with passive oxygenation/ventilation: a METI HPS study

“…This finding is in accordance with that by Lejus et al., 20 who described a delayed decrease in S p O 2 during apnea on the METI HPS in comparison with a clinical situation. Both the shape and values of the S p O 2 curve (desaturating part of curve) in the present study are similar to those reported by Chandra et al., 25 who examined the S p O 2 values in canines (93.9 ± 2.8 at 4 min and 70.4 ± 10.6 at 10 min) after chest compression-only resuscitation. In contrast, significantly lower S p O 2 values were observed (6 ± 4 at 3 min and 4 ± 1 at 9 min) in pigs resuscitated with only chest compressions, also resulting in a steeper decrease in the desaturation part of the S p O 2 curve.…”

“…The same decline in P a O 2 was described by Chandra et al. 25 with a similar value of P a O 2 (40.9 ± 7.5 mmHg) 10 minutes after chest compression-only CPR.…”

“…In the present study, P a O 2 started to fall only after the beginning of the chest compression period. The same decline in P a O 2 was described by Chandra et al 25 with a similar value of P a O 2 (40.9 AE 7.5 mmHg) 10 minutes after chest compression-only CPR.…”

“…27 reported lower values of P a CO 2 in animal studies (38.8 ± 6.4 mmHg after 10 min and 41 ± 12 mmHg after 4 min of chest compression-only CPR). This difference may be due to the lower baseline (prearrest) values of P a CO 2 in canines (27 ± 1.5 mmHg) 25 and shorter period of cardiac arrest (2 min) 25,27 compared with our study. Dorph et al.…”

“…The pattern of changes in P a CO 2 during the chest compression-only CPR period of the present study is in accordance with previously published animal studies. 25,26 However, Chandra et al 25 and Berg et al 27 25 and shorter period of cardiac arrest (2 min) 25,27 compared with our study. Dorph et al 26 observed significantly higher levels of carbon dioxide (92.5 mmHg after 9 minutes of chest compression-only CPR) in pigs with obstructed airway, which prevented passive ventilation and resulted in higher values of P a CO 2 .…”

Arterial blood gas changes during cardiac arrest and cardiopulmonary resuscitation combined with passive oxygenation/ventilation: a METI HPS study

“…This finding is in accordance with that by Lejus et al., 20 who described a delayed decrease in S p O 2 during apnea on the METI HPS in comparison with a clinical situation. Both the shape and values of the S p O 2 curve (desaturating part of curve) in the present study are similar to those reported by Chandra et al., 25 who examined the S p O 2 values in canines (93.9 ± 2.8 at 4 min and 70.4 ± 10.6 at 10 min) after chest compression-only resuscitation. In contrast, significantly lower S p O 2 values were observed (6 ± 4 at 3 min and 4 ± 1 at 9 min) in pigs resuscitated with only chest compressions, also resulting in a steeper decrease in the desaturation part of the S p O 2 curve.…”

“…The same decline in P a O 2 was described by Chandra et al. 25 with a similar value of P a O 2 (40.9 ± 7.5 mmHg) 10 minutes after chest compression-only CPR.…”

“…In the present study, P a O 2 started to fall only after the beginning of the chest compression period. The same decline in P a O 2 was described by Chandra et al 25 with a similar value of P a O 2 (40.9 AE 7.5 mmHg) 10 minutes after chest compression-only CPR.…”

“…27 reported lower values of P a CO 2 in animal studies (38.8 ± 6.4 mmHg after 10 min and 41 ± 12 mmHg after 4 min of chest compression-only CPR). This difference may be due to the lower baseline (prearrest) values of P a CO 2 in canines (27 ± 1.5 mmHg) 25 and shorter period of cardiac arrest (2 min) 25,27 compared with our study. Dorph et al.…”

“…The pattern of changes in P a CO 2 during the chest compression-only CPR period of the present study is in accordance with previously published animal studies. 25,26 However, Chandra et al 25 and Berg et al 27 25 and shorter period of cardiac arrest (2 min) 25,27 compared with our study. Dorph et al 26 observed significantly higher levels of carbon dioxide (92.5 mmHg after 9 minutes of chest compression-only CPR) in pigs with obstructed airway, which prevented passive ventilation and resulted in higher values of P a CO 2 .…”

Arterial blood gas changes during cardiac arrest and cardiopulmonary resuscitation combined with passive oxygenation/ventilation: a METI HPS study

“…This finding is in accordance with that by Lejus et al., 20 who described a delayed decrease in S p O 2 during apnea on the METI HPS in comparison with a clinical situation. Both the shape and values of the S p O 2 curve (desaturating part of curve) in the present study are similar to those reported by Chandra et al., 25 who examined the S p O 2 values in canines (93.9 ± 2.8 at 4 min and 70.4 ± 10.6 at 10 min) after chest compression-only resuscitation. In contrast, significantly lower S p O 2 values were observed (6 ± 4 at 3 min and 4 ± 1 at 9 min) in pigs resuscitated with only chest compressions, also resulting in a steeper decrease in the desaturation part of the S p O 2 curve.…”

“…The same decline in P a O 2 was described by Chandra et al. 25 with a similar value of P a O 2 (40.9 ± 7.5 mmHg) 10 minutes after chest compression-only CPR.…”

“…In the present study, P a O 2 started to fall only after the beginning of the chest compression period. The same decline in P a O 2 was described by Chandra et al 25 with a similar value of P a O 2 (40.9 AE 7.5 mmHg) 10 minutes after chest compression-only CPR.…”

“…27 reported lower values of P a CO 2 in animal studies (38.8 ± 6.4 mmHg after 10 min and 41 ± 12 mmHg after 4 min of chest compression-only CPR). This difference may be due to the lower baseline (prearrest) values of P a CO 2 in canines (27 ± 1.5 mmHg) 25 and shorter period of cardiac arrest (2 min) 25,27 compared with our study. Dorph et al.…”

“…The pattern of changes in P a CO 2 during the chest compression-only CPR period of the present study is in accordance with previously published animal studies. 25,26 However, Chandra et al 25 and Berg et al 27 25 and shorter period of cardiac arrest (2 min) 25,27 compared with our study. Dorph et al 26 observed significantly higher levels of carbon dioxide (92.5 mmHg after 9 minutes of chest compression-only CPR) in pigs with obstructed airway, which prevented passive ventilation and resulted in higher values of P a CO 2 .…”

Arterial blood gas changes during cardiac arrest and cardiopulmonary resuscitation combined with passive oxygenation/ventilation: a METI HPS study

“…This finding is in accordance with that by Lejus et al., 20 who described a delayed decrease in S p O 2 during apnea on the METI HPS in comparison with a clinical situation. Both the shape and values of the S p O 2 curve (desaturating part of curve) in the present study are similar to those reported by Chandra et al., 25 who examined the S p O 2 values in canines (93.9 ± 2.8 at 4 min and 70.4 ± 10.6 at 10 min) after chest compression-only resuscitation. In contrast, significantly lower S p O 2 values were observed (6 ± 4 at 3 min and 4 ± 1 at 9 min) in pigs resuscitated with only chest compressions, also resulting in a steeper decrease in the desaturation part of the S p O 2 curve.…”

“…The same decline in P a O 2 was described by Chandra et al. 25 with a similar value of P a O 2 (40.9 ± 7.5 mmHg) 10 minutes after chest compression-only CPR.…”

“…In the present study, P a O 2 started to fall only after the beginning of the chest compression period. The same decline in P a O 2 was described by Chandra et al 25 with a similar value of P a O 2 (40.9 AE 7.5 mmHg) 10 minutes after chest compression-only CPR.…”

“…27 reported lower values of P a CO 2 in animal studies (38.8 ± 6.4 mmHg after 10 min and 41 ± 12 mmHg after 4 min of chest compression-only CPR). This difference may be due to the lower baseline (prearrest) values of P a CO 2 in canines (27 ± 1.5 mmHg) 25 and shorter period of cardiac arrest (2 min) 25,27 compared with our study. Dorph et al.…”

“…The pattern of changes in P a CO 2 during the chest compression-only CPR period of the present study is in accordance with previously published animal studies. 25,26 However, Chandra et al 25 and Berg et al 27 25 and shorter period of cardiac arrest (2 min) 25,27 compared with our study. Dorph et al 26 observed significantly higher levels of carbon dioxide (92.5 mmHg after 9 minutes of chest compression-only CPR) in pigs with obstructed airway, which prevented passive ventilation and resulted in higher values of P a CO 2 .…”