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Cited by 49 publications
(35 citation statements)
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“…These results indicate that 3D collagen scaffolds may provide a useful platform for anti-cancer therapeutics and CSC research. Furthermore, breast cancer stem cell expansion in PCL scaffolds (83), ovarian cancer stem cell behavior and drug resistance investigated in 3D basement membrane extract scaffolds (84) and glioma stem cells proliferating in 3D chitosan-alginate scaffolds (85) were observed in these studies, sequentially.…”
Section: Multicellular Tumor Spheroids (Mcts)mentioning
confidence: 82%
“…These results indicate that 3D collagen scaffolds may provide a useful platform for anti-cancer therapeutics and CSC research. Furthermore, breast cancer stem cell expansion in PCL scaffolds (83), ovarian cancer stem cell behavior and drug resistance investigated in 3D basement membrane extract scaffolds (84) and glioma stem cells proliferating in 3D chitosan-alginate scaffolds (85) were observed in these studies, sequentially.…”
Section: Multicellular Tumor Spheroids (Mcts)mentioning
confidence: 82%
“…However, the relevance of IL-17A with drug-resistance of OVCA has not been clear until now. Increasing evidences showed that the up-regulating of ABC proteins such as ABCG2 and MDR1 are involved in cisplatin-induced resistance [41,42]. Literatures also reported that DDP exerts cytotoxicity via inducing apoptosis [33,34].…”
Section: Discussionmentioning
confidence: 99%
“…Cells cultured in 2D do not, however, recapitulate the cellular architecture, that is, critical for accurately modeling tumor growth and response to therapies [25, 26]. In contrast, 3D models predict resistance to chemo- and radiation therapies [2729]. Hasan and colleagues have adapted ovarian and pancreatic cancer cells to 3D models to evaluate PDT in photokilling these resistant cancer cells [3032].…”
Section: Introductionmentioning
confidence: 99%