2016
DOI: 10.1590/0102-311xed010916
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Abstract: The search for critical syntheses of scientific knowledge is not new. For example, 18 th -century Scottish physician James Lind, credited with the first clinical trial in medicine 1 , stated on the cover page of his A Treatise of the Scurvy that it contained "an inquiry into the nature, causes and cure, of that disease. Together with a critical and chronological view of what has been published on the subject" 2 (p. 13-4). The first attempt to quantitatively combine the results of different health studies is a…

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