volume 82, issue 4, P1194-1198 1985
DOI: 10.1073/pnas.82.4.1194
View full text
|
Sign up to set email alerts
|
Share

Abstract: ABSTRACTA system for the production of monoclonal antibodies, particularly of the IgG type, against weakly immunogenic bacterial polysaccharide antigens is described. This system, which is based on the autoimmune NZB mouse strain, has been used to produce a monoclonal IgG2a antibody against the meningococcus group B and Escherichia coli K1 polysaccharides, identical homopolymers of a(2-+8)-linked units ofNacetylneuraminic acid that are extremely poor immunogens.Comparison of the humoral immune responses of no…

Expand abstract

Search citation statements

Order By: Relevance

Citation Types

1
204
0

Paper Sections

0
0
0
0
0

Publication Types

0
0
0
0

Relationship

0
0

Authors

Journals