Nutrition and Developmental Origins of Kidney Disease
Long T. Nguyen,
Carol A. Pollock,
Sonia Saad
Abstract:The developmental programming hypothesis proposes that adverse environmental insults during critical developmental periods increase the risk of diseases later in life. The kidneys are deemed susceptible to such a process, although the exact mechanisms remain elusive. Many factors have been reported to contribute to the developmental origin of chronic kidney diseases (CKD), among which peri-gestational nutrition has a central role, affecting kidney development and metabolism. Physiologically, the link between m… Show more
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