Nummular Eczema

Cutaneous Manifestations of Porphyria

“…The combination of exposure to sunlight and liver damage may account for the high frequency of the disease found in South Africa by Barnes. Conigenital Nature of the Disease.-Porphyric bullous dermatosis is a familial disease. Urbach (1937, Case 1) notes the disease in father and son; Gross (1910) and Hudelo and Montlaur (1919) describe cases in brothers and sisters, while Anderson (1898), Templeton and Lunsford (1932), and Brunsting andMason (1946, 1949) record cases in which the patient's mother or sister was symptom-free though excreting porphyrin. Borzow (1933) and Calvy et al (1951) describe families with symptoms in sibs of four or five generations.…”

Nummular eczema--clinical and statistical data.

“…From figures 1 and 2 can be seen, that the most common agc of onset for nummular eczema in males is between 35-70 years of age with a maximum in the age group 55-65 ycars of age. That the onset of the dis ease of ten occurs at older age can be ex plained by the fact that peoplc often havc a more dry skin at this age; Gross is of the opinion that there is a pathogenetic associa tion bctween dry skin and nummular ec zema, and that dry skin might predispose to nummular eczema (6). The importance of dry skin is also mentioned by Hagerman (ro).…”

“…During the last twenty years reports i.a. from Gross in the U.S.A. (6)(7)(8)(9) 1 Cowen in England (3), Krogh in Norway (16) 1 Braun-Falco (2) and Röckl and Schröpfl in Germany ( c8) have madc important contributions to the knowledge of this discase.…”