Numerical investigations on the strain-adaptive bone remodelling in the periprosthetic femur: Influence of the boundary conditions

Behrens, Bernd‐Arno; Nolte, Ingo; Wefstaedt, Patrick; Stukenborg-Colsman, Christina; Bouguecha, Anas

doi:10.1186/1475-925x-8-7

Cited by 74 publications

(57 citation statements)

References 27 publications

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“…1 (a)) in order to achieve an accurate measuring of the BMD and its changings during the study period [4]. The FE-model of the periprosthetic femur used at IFUM in [5,6,7] is used in this comparison applying the same conditions and constraints with the same muscle forces and hip contacts but with the following restrictions:…”

Section: Methodsmentioning

confidence: 99%

Comparison between simulation results and DEXA investigation of the bone remodelling after implanting a cementless long stem hip prosthesis

Almohallami¹,

Bouguecha²,

Stukenborg-Colsman³

et al. 2013

Biomedical Engineering / Biomedizinische Technik

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Section: Methodsmentioning

confidence: 99%

Comparison between simulation results and DEXA investigation of the bone remodelling after implanting a cementless long stem hip prosthesis

Almohallami¹,

Bouguecha²,

Stukenborg-Colsman³

et al. 2013

Biomedical Engineering / Biomedizinische Technik

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“…Since the publication of the first bone remodelling simulations around implants by Huiskes and co-workers (Huiskes, 1988), there have only been incremental developments, for example accounting for overload induced bone loss (Behrens et al, 2009;Scannell and Prendergast, 2009). These tools are still phenomenological descriptions of bone remodelling and different stimuli have been shown to result in similar predictions of adaptation (Schmitz et al, 2004).…”

Section: Time Dependent/adaptive Modelling Techniquesmentioning

confidence: 99%

“…The main focus of this review will be hip and knee replacement, as these have been studied the most, but the issues raised are applicable to the simulation of all orthopaedic devices. FE models have grown in both size and sophistication and techniques exist to assess the initial post-op mechanical environment Zivkovic et al, 2010;Chong et al, 2010;Pettersen et al, 2009;Reggiani et al, 2008;Udofia et al, 2007;Spears et al, 2001;Baldwin et al, 2008;Godest et al, 2002;Taylor and Barrett 2003;Perillo-Marcone and Taylor 2007;Chang et al, 2001) through to the simulation of time dependent processes including bone remodelling induced stress shielding (Huiskes et al, 1987;Perez et al, 2010;Behrens et al, 2009;Gillies et al, 2007;Taylor et al, 2004;McNamara et al, 1997;Weinans et al, 1994;Rietbergen et al, 1993;Gupta et al, 2006), tissue adaptation Andreykiv et al, 2005;Simmons et al, 2001), wear (Strickland et al, 2011;Strickland and Taylor 2009;Knight et al, 2007;Fregly et al, 2005;Bevill et al, 2005;Teoh et al, 2002;Brown et al, 2002;Maxian et al, 1996;Pal et al, 2008), damage accumulation of the cement mantle (Coultrup et al, 2010;Janssen et al, 2009;Lennon et al, 2007;Jeffers et al, 2007;Janssen et al, 2006;…”

Section: Introductionmentioning

confidence: 99%

Four decades of finite element analysis of orthopaedic devices: Where are we now and what are the opportunities?

Taylor

Prendergast

2015

Journal of Biomechanics

140

106

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a b s t r a c tFinite element has been used for more than four decades to study and evaluate the mechanical behaviour total joint replacements. In Huiskes seminal paper "Failed innovation in total hip replacement: diagnosis and proposals for a cure", finite element modelling was one of the potential cures to avoid poorly performing designs reaching the market place. The size and sophistication of models has increased significantly since that paper and a range of techniques are available from predicting the initial mechanical environment through to advanced adaptive simulations including bone adaptation, tissue differentiation, damage accumulation and wear. However, are we any closer to FE becoming an effective screening tool for new devices? This review contains a critical analysis of currently available finite element modelling techniques including (i) development of the basic model, the application of appropriate material properties, loading and boundary conditions, (ii) describing the initial mechanical environment of the bone-implant system, (iii) capturing the time dependent behaviour in adaptive simulations, (iv) the design and implementation of computer based experiments and (v) determining suitable performance metrics.The development of the underlying tools and techniques appears to have plateaued and further advances appear to be limited either by a lack of data to populate the models or the need to better understand the fundamentals of the mechanical and biological processes. There has been progress in the design of computer based experiments. Historically, FE has been used in a similar way to in vitro tests, by running only a limited set of analyses, typically of a single bone segment or joint under idealised conditions. The power of finite element is the ability to run multiple simulations and explore the performance of a device under a variety of conditions. There has been increasing usage of design of experiments, probabilistic techniques and more recently population based modelling to account for patient and surgical variability. In order to have effective screening methods, we need to continue to develop these approaches to examine the behaviour and performance of total joint replacements and benchmark them for devices with known clinical performance.Finite element will increasingly be used in the design, development and pre-clinical testing of total joint replacements. However, simulations must include holistic, closely corroborated, multi-domain analyses which account for real world variability.

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“…A prognosis concerning changes in bone morphology under mechanical stress can be ventured using a time-step method based on standard computer tomography (CT) datasets and finite element analysis (FEA) [1][2][3]. Following this theory, the aim of our work was the development of a numerical algorithm to simulate the mechanically stimulated bone remodelling.…”

Section: Introductionmentioning

confidence: 99%

Numerical simulation of mechanically stimulated bone remodelling

Mauck

Wieding

Kluess

et al. 2016

Current Directions in Biomedical Engineering

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Abstract:The numerical simulation of bone remodelling provides a great opportunity to improve the choice of therapy in particular for complex bone defects. Despite this fact, its use in clinical practice is not yet expedient because of several unresolved problems. In this paper a new bone remodelling algorithm based on standard computer tomography datasets and finite element analysis is introduced.

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Numerical investigations on the strain-adaptive bone remodelling in the periprosthetic femur: Influence of the boundary conditions

Cited by 74 publications

References 27 publications

Comparison between simulation results and DEXA investigation of the bone remodelling after implanting a cementless long stem hip prosthesis

Comparison between simulation results and DEXA investigation of the bone remodelling after implanting a cementless long stem hip prosthesis

Four decades of finite element analysis of orthopaedic devices: Where are we now and what are the opportunities?

Numerical simulation of mechanically stimulated bone remodelling

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